Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling
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Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signalingSecreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cellsSecreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signalingSecreted frizzled-related protein 1 (SFRP1) protects fibroblasts from ceramide-induced apoptosisA novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signalingMutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerizationRegulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formationRegulation of secreted Frizzled-related protein-1 by heparinThe human Frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt. beta-catenin signaling cascadeMethylation-associated silencing of SFRP1 with an 8p11-12 amplification inhibits canonical and non-canonical WNT pathways in breast cancersA novel mechanism for Wnt activation of canonical signaling through the LRP6 receptorSecreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agentSecreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancerSoluble frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesisIncreased expression of secreted frizzled-related protein 4 in polycystic kidneysModular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1Role of epigenetic alterations in the pathogenesis of Barrett's esophagus and esophageal adenocarcinomaFrizzled7: A Promising Achilles' Heel for Targeting the Wnt Receptor Complex to Treat CancerA cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signalingSecreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signalingWNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary typeAutocrine/paracrine secreted Frizzled-related protein 2 induces cellular resistance to apoptosis: a possible mechanism of mammary tumorigenesisDeletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancerExpression of the secreted frizzled-related protein gene family is downregulated in human mesotheliomaSFRP1 is a possible candidate for epigenetic therapy in non-small cell lung cancerRegulation of Wnt/β-catenin signaling within and from osteocytesThe frizzled-related sFRP2 gene is a target of thyroid hormone receptor alpha1 and activates beta-catenin signaling in mouse intestineSexually dimorphic expression of secreted frizzled-related (SFRP) genes in the developing mouse Müllerian ductTranscriptional regulation of the promoter of the rat frizzled related protein gene by CREBPlacental expression of secreted frizzled related protein-4 in the rat and the impact of glucocorticoid-induced fetal and placental growth restrictionSFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cellsSystems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney diseaseInhibition of canonical Wnt signaling increases microvascular hemorrhaging and venular remodeling in adult ratsWnt5a induces simultaneous cortical axon outgrowth and repulsive axon guidance through distinct signaling mechanisms.Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling.Regulation of a multigenic invasion programme by the transcription factor, AP-1: re-expression of a down-regulated gene, TSC-36, inhibits invasion.Binding of sFRP-3 to EGF in the extra-cellular space affects proliferation, differentiation and morphogenetic events regulated by the two molecules.Secreted frizzled-related protein 4: an angiogenesis inhibitor.The effects of diet induced obesity on breast cancer associated pathways in mice deficient in SFRP1.Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways.
P2860
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P248
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P2860
Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@ast
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@en
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@en-gb
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@nl
type
label
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@ast
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@en
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@en-gb
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@nl
prefLabel
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@ast
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@en
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@en-gb
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@nl
P2093
P921
P3181
P356
P1476
Interaction of frizzled relate ...... RP inhibition of Wnt signaling
@en
P2093
P304
P3181
P356
10.1074/JBC.274.23.16180
P407
P577
1999-06-04T00:00:00Z