Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)
about
Mechanisms for the modulation of dopamine d(1) receptor signaling in striatal neuronsIsolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expressionDistinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatumBinding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activityEvaluating the antipsychotic profile of the preferential PDE10A inhibitor, papaverinePotential role of phosphodiesterase 7 in human T cell function: comparative effects of two phosphodiesterase inhibitorsNovel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012Structural insight into substrate specificity of phosphodiesterase 10Crystal structure of the GAF-B domain from human phosphodiesterase 10A complexed with its ligand, cAMPThe human phosphodiesterase PDE10A gene genomic organization and evolutionary relatedness with other PDEs containing GAF domainsGenomic organization of the human phosphodiesterase PDE11A gene. Evolutionary relatedness with other PDEs containing GAF domainsExpression and functional activity of phosphodiesterase type 5 in human and rabbit vas deferensStriatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicityIdentification and characterization of DdPDE3, a cGMP-selective phosphodiesterase from DictyosteliumDifferential changes in amygdala and frontal cortex Pde10a expression during acute and protracted withdrawalInhibition of phosphodiesterase 10A has differential effects on dopamine D1 and D2 receptor modulation of sensorimotor gating.Phosphodiesterase 10A regulates alcohol and saccharin self-administration in ratsRadiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primateCross-regulation of Phosphodiesterase 1 and Phosphodiesterase 2 Activities Controls Dopamine-mediated Striatal α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor TraffickingPhosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in StriatumPDE10A inhibitors stimulate or suppress motor behavior dependent on the relative activation state of the direct and indirect striatal output pathwaysSubcellular localization of cyclic nucleotide phosphodiesterase type 10A variants, and alteration of the localization by cAMP-dependent protein kinase-dependent phosphorylationNovel alternative splice variants of rat phosphodiesterase 7B showing unique tissue-specific expression and phosphorylationcGMP-phosphodiesterase activity is up-regulated in response to pressure overload of rat ventriclesStriatum- and testis-specific phosphodiesterase PDE10A isolation and characterization of a rat PDE10ACellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesteraseCyclic AMP control measured in two compartments in HEK293 cells: phosphodiesterase K(M) is more important than phosphodiesterase localizationMolecular Imaging Markers to Track Huntington’s Disease PathologyStress history increases alcohol intake in relapse: relation to phosphodiesterase 10A.The Concise Guide to PHARMACOLOGY 2013/14: enzymes.Characterization of TbPDE2A, a novel cyclic nucleotide-specific phosphodiesterase from the protozoan parasite Trypanosoma brucei.Effect of chronic antipsychotic treatment on striatal phosphodiesterase 10A levels: a [¹¹C]MP-10 PET rodent imaging study with ex vivo confirmation.Characterization of novel phosphodiesterases in the bovine ovarian follicleStriatal Vulnerability in Huntington's Disease: Neuroprotection Versus Neurotoxicity.Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodelingcGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activityDdPDE4, a novel cAMP-specific phosphodiesterase at the surface of dictyostelium cells.Longitudinal behavioral, cross-sectional transcriptional and histopathological characterization of a knock-in mouse model of Huntington's disease with 140 CAG repeats.Anti-spasmogenic activity of isoenzyme-selective phosphodiesterase inhibitors in guinea-pig trachealis.
P2860
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P2860
Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@ast
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@en
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@en-gb
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@nl
type
label
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@ast
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@en
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@en-gb
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@nl
prefLabel
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@ast
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@en
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@en-gb
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@nl
P2093
P2860
P3181
P356
P1476
Cloning and characterization o ...... es both cAMP and cGMP (PDE10A)
@en
P2093
H Michibata
K Fujishige
S Takebayashi
P2860
P304
P3181
P356
10.1074/JBC.274.26.18438
P407
P577
1999-06-25T00:00:00Z