p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53
about
Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradationA C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism.Complex transcriptional effects of p63 isoforms: identification of novel activation and repression domainsMicroRNA 203 expression in keratinocytes is dependent on regulation of p53 levels by E6Caught in self-interaction: evolutionary and functional mechanisms of protein homooligomerizationActivation of p53 in cervical carcinoma cells by small molecules.Oncogenic Intra-p53 Family Member Interactions in Human CancersElectrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomicsStructural evolution of p53, p63, and p73: Implication for heterotetramer formationStructure and Kinetic Stability of the p63 Tetramerization DomainGPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent mannerNickel-induced down-regulation of ΔNp63 and its role in the proliferation of keratinocytesdeltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytesp73 as a pharmaceutical target for cancer therapyAmphiphysin IIb-1, a novel splicing variant of amphiphysin II, regulates p73beta function through protein-protein interactions.More targets, more pathways and more clues for mutant p53.Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway.TP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy.p73 competes with p53 and attenuates its response in a human ovarian cancer cell line.p73: structure and function.Mechanisms of regulatory diversity within the p53 transcriptional network.p53 associates with and targets Delta Np63 into a protein degradation pathwaySynthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.p53 Isoforms: An Intracellular Microprocessor?p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasisAutoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoterThe role of tetramerization in p53 function.p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network.Role of p73 in malignancy: tumor suppressor or oncogene?Evolutionary, physicochemical, and functional mechanisms of protein homooligomerization.The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutationsMutant p53: one name, many proteins.Role of p63 in Development, Tumorigenesis and Cancer ProgressionΔNp63α utilizes multiple mechanisms to repress transcription in squamous cell carcinoma cells.Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?Cataloging and organizing p73 interactions in cell cycle arrest and apoptosisTherapeutic prospects for p73 and p63: rising from the shadow of p53.How many mutant p53 molecules are needed to inactivate a tetramer?The alpha/beta carboxy-terminal domains of p63 are required for skin and limb development. New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 gamma-like proteinsMutant p53 mediates survival of breast cancer cells
P2860
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P2860
p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
p73 and p63 are homotetramers ...... th each other but not with p53
@ast
p73 and p63 are homotetramers ...... th each other but not with p53
@en
p73 and p63 are homotetramers ...... th each other but not with p53
@en-gb
p73 and p63 are homotetramers ...... th each other but not with p53
@nl
type
label
p73 and p63 are homotetramers ...... th each other but not with p53
@ast
p73 and p63 are homotetramers ...... th each other but not with p53
@en
p73 and p63 are homotetramers ...... th each other but not with p53
@en-gb
p73 and p63 are homotetramers ...... th each other but not with p53
@nl
prefLabel
p73 and p63 are homotetramers ...... th each other but not with p53
@ast
p73 and p63 are homotetramers ...... th each other but not with p53
@en
p73 and p63 are homotetramers ...... th each other but not with p53
@en-gb
p73 and p63 are homotetramers ...... th each other but not with p53
@nl
P2093
P2860
P921
P3181
P356
P1476
p73 and p63 are homotetramers ...... th each other but not with p53
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.274.26.18709
P407
P577
1999-06-25T00:00:00Z