Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
about
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) familySites of aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4)Identification, characterization, and intracellular processing of ADAM-TS12, a novel human disintegrin with a complex structural organization involving multiple thrombospondin-1 repeatsStructure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpuraRegulated expression of ADAMTS-12 in human trophoblastic cells: a role for ADAMTS-12 in epithelial cell invasion?Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi networkC-terminal ADAMTS-18 fragment induces oxidative platelet fragmentation, dissolves platelet aggregates, and protects against carotid artery occlusion and cerebral strokeInhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulinADAMTS-12 associates with and degrades cartilage oligomeric matrix proteinADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulationCharacterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1Sodium and T1rho MRI for molecular and diagnostic imaging of articular cartilageCrystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5VLA-4-dependent and -independent pathways in cell contact-induced proinflammatory cytokine production by synovial nurse-like cells from rheumatoid arthritis patientsAggrecanases and cartilage matrix degradationFunctional evolution of ADAMTS genes: evidence from analyses of phylogeny and gene organizationArticular cartilage and changes in arthritis: matrix degradation.Advances in understanding cartilage remodelingStructural and Inhibition Analysis Reveals the Mechanism of Selectivity of a Series of Aggrecanase InhibitorsHigh resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2)Structure analysis reveals the flexibility of the ADAMTS-5 active siteTransforming growth factor-beta induces secretion of activated ADAMTS-2. A procollagen III N-proteinase.Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP)ADAMTS-1 cleaves a cartilage proteoglycan, aggrecanAspartyl beta -hydroxylase (Asph) and an evolutionarily conserved isoform of Asph missing the catalytic domain share exons with junctinVersican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinomaDiscovery and characterization of a novel, widely expressed metalloprotease, ADAMTS10, and its proteolytic activationTransgenic mice with inactive alleles for procollagen N-proteinase (ADAMTS-2) develop fragile skin and male sterilityADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domainAdamts-1 is essential for the development and function of the urogenital systemIdentification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domainThe ADAMTS metalloproteinasesHow matrix metalloproteinases regulate cell behaviorStall encodes an ADAMTS metalloprotease and interacts genetically with Delta in Drosophila ovarian follicle formation.Pathologic indicators of degradation and inflammation in human osteoarthritic cartilage are abrogated by exposure to n-3 fatty acids.Catabolism of aggrecan, decorin and biglycan in tendon.ADAMTS4 (aggrecanase-1) interaction with the C-terminal domain of fibronectin inhibits proteolysis of aggrecan.Expression and activity of ADAMTS-5 in synovium.
P2860
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P2860
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@ast
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@en
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@en-gb
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@nl
type
label
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@ast
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@en
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@en-gb
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@nl
prefLabel
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@ast
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@en
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@en-gb
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@nl
P2093
P2860
P356
P1476
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
@en
P2093
B H Wiswall
C P Decicco
H J George
I Abbaszade
J M Hollis
J M Trzaskos
P2860
P304
23443-23450
P356
10.1074/JBC.274.33.23443
P407
P577
1999-08-01T00:00:00Z