Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
about
MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genesATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1Identification of a novel thioredoxin-related transmembrane proteinIdentification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein responseCREB-H: a novel mammalian transcription factor belonging to the CREB/ATF family and functioning via the box-B element with a liver-specific expressionEndoplasmic reticulum stress and Parkinson's disease: the role of HRD1 in averting apoptosis in neurodegenerative diseaseATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase geneNck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stressWolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cellsLuman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response elementEDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming stepTranscriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle traffickingTBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stressA ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of ParkinInduction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elementsGlobal proteomic approach unmasks involvement of keratins 8 and 18 in the delivery of cystic fibrosis transmembrane conductance regulator (CFTR)/deltaF508-CFTR to the plasma membraneA novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein responseHeat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha.Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradationCREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P.Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stressDistinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein responseLuman, the cellular counterpart of herpes simplex virus VP16, is processed by regulated intramembrane proteolysisHepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathwayEndoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein responseS phase-specific proteolytic cleavage is required to activate stable DNA binding by the CDP/Cut homeodomain proteinIdentification of TFII-I as the endoplasmic reticulum stress response element binding factor ERSF: its autoregulation by stress and interaction with ATF6.Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicingN-terminal transcriptional activation domain of LZIP comprises two LxxLL motifs and the host cell factor-1 binding motifCellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegenerationIRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein responseUnfolded protein response in a Drosophila model for retinal degenerationConsensus clustering and functional interpretation of gene-expression dataIRE1-independent gain control of the unfolded protein responseGcn4p and novel upstream activating sequences regulate targets of the unfolded protein responseComputational prediction of membrane-tethered transcription factorsGenome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nucleaseThe liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinomaMapping and characterization of the amplicon near APOA2 in 1q23 in human sarcomas by FISH and array CGHGenetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans.
P2860
Q21090170-C6114645-9FC3-4976-925F-6E55E10C2E52Q22254333-E4C776D3-1ED7-43EA-8416-14683317AB2BQ24290725-8CEFAB07-0AD9-4188-A84E-17D3AE506C90Q24290935-E1827160-7C9C-4734-AED8-AA5E4975A3DDQ24291231-46A3D885-9047-46A5-8268-9782616F259DQ24293694-E5FF9FBE-8F1C-43E7-B0A7-1C08BC3D1B15Q24294712-4FEB8CF8-970D-41F5-94EB-80ACC1BECC25Q24296809-52082A89-3C60-4BF1-9F7C-8FAFE932E63BQ24299603-0D8F99E9-DE58-4450-A719-5C198A3B7902Q24301000-521754A8-F03F-4CD4-94F5-8846511CC071Q24301651-FD304CBC-7FDC-49E9-81CA-29940C812BB6Q24303861-F0B2194A-6641-4C3A-984A-334D0CADD45DQ24306638-280E868A-317A-49AF-B653-6AC862AD23C0Q24308676-ABB6AE8C-C403-4F07-997D-A77B86BBF8CFQ24310021-D80DF45F-C209-46AE-875F-8F24C9936F4CQ24312150-E0F2163F-B45C-4A90-A69C-D6AE64929C6AQ24317491-50DB21F3-F54B-4CFB-B44F-583143A0C3FEQ24320638-0AA8D072-1CBD-48B3-9835-F87C4309C21DQ24322671-E0A03E22-7A69-4208-B606-E2DE01E1DB25Q24338672-493B8D19-235F-435F-8003-9110D7F4D649Q24529972-66D9A63C-B270-4AE3-A092-3EE2D78AB20EQ24534422-D688A641-96A1-4F46-9882-BDCFB53A00EDQ24537679-B205B789-15DD-409B-8A33-A3A9C7DED951Q24537844-A608D77F-E587-4A0E-95BB-CB39DFB5015AQ24548363-072C2DF1-3F0A-44E1-8B81-2F253BA81606Q24550847-0E21C8AA-2CCA-409A-B773-8ED151C8288AQ24550967-1FF06B75-5357-4072-82CB-4BA2E481451CQ24627782-88171D1F-5573-4EB6-8E92-0439E9D42D82Q24649820-32949F71-E6A8-4D9C-A887-7C47B5188BBAQ24654460-8BD02B03-6377-4B9E-9D4C-083D0847C234Q24672592-787CD087-F5FE-4432-9E66-7B184577D504Q24682908-EE5AE1E3-D3FC-48DF-8789-E631C5E8BE43Q24791011-48B1102B-8E79-4410-B17B-4AAFBCA3BA86Q24798921-6037953F-4545-450C-981A-32DE2F4D687AQ24799136-8335EFF1-BA4A-4DE1-AD51-D10F6D827D05Q24799487-A2B9A47A-60D1-4C14-A2D4-4FC142ACC140Q24805574-FB2D6338-8FEF-400F-8CD2-3C0A77C0BC7EQ24805822-12ACFA4D-FDC5-4ED9-A389-BE4E850362D5Q24815629-C3764ACE-4961-483B-85A5-9EC2DEEA38DAQ24815740-BBFB8901-705C-490F-AA9E-8FDEA0370981
P2860
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mammalian transcription factor ...... o endoplasmic reticulum stress
@ast
Mammalian transcription factor ...... o endoplasmic reticulum stress
@en
Mammalian transcription factor ...... o endoplasmic reticulum stress
@en-gb
Mammalian transcription factor ...... o endoplasmic reticulum stress
@nl
type
label
Mammalian transcription factor ...... o endoplasmic reticulum stress
@ast
Mammalian transcription factor ...... o endoplasmic reticulum stress
@en
Mammalian transcription factor ...... o endoplasmic reticulum stress
@en-gb
Mammalian transcription factor ...... o endoplasmic reticulum stress
@nl
prefLabel
Mammalian transcription factor ...... o endoplasmic reticulum stress
@ast
Mammalian transcription factor ...... o endoplasmic reticulum stress
@en
Mammalian transcription factor ...... o endoplasmic reticulum stress
@en-gb
Mammalian transcription factor ...... o endoplasmic reticulum stress
@nl
P2093
P2860
P921
P3181
P356
P1476
Mammalian transcription factor ...... o endoplasmic reticulum stress
@en
P2093
P2860
P304
P3181
P356
10.1091/MBC.10.11.3787
P407
P577
1999-11-01T00:00:00Z