Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels
about
Expanding the clinical spectrum associated with defects in CNTNAP2 and NRXN1Advances in autism genetics: on the threshold of a new neurobiologySpectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissuesCNTNAP2 and NRXN1 are mutated in autosomal-recessive Pitt-Hopkins-like mental retardation and determine the level of a common synaptic protein in DrosophilaJuxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotoniaA common genetic variant in the neurexin superfamily member CNTNAP2 increases familial risk of autismNogo-A at CNS paranodes is a ligand of Caspr: possible regulation of K(+) channel localization[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of RanvierSodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapsesCaspr regulates the processing of contactin and inhibits its binding to neurofascinDistinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cellsAssociation of TAG-1 with Caspr2 is essential for the molecular organization of juxtaparanodal regions of myelinated fibersCandidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine developmentPediatric Autoimmune Disorders Associated with Streptococcal Infections and Tourette's Syndrome in Preclinical Studies.Clinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.Mouse Genetic Models of Human Brain DisordersFunctional Evaluations of Genes Disrupted in Patients with Tourette's Disorder.Striatal Circuits as a Common Node for Autism PathophysiologyBehavioral phenotypes of genetic mouse models of autism.New insights into the pathogenesis and therapeutics of episodic ataxia type 1Myelin damage and repair in pathologic CNS: challenges and prospectsAutoimmune encephalitis in psychiatric institutions: current perspectivesConnecting the CNTNAP2 Networks with Neurodevelopmental DisordersProtein 4.1B associates with both Caspr/paranodin and Caspr2 at paranodes and juxtaparanodes of myelinated fibresADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axonsOpalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membraneA glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of RanvierMultiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axonsUsing Gene Ontology to describe the role of the neurexin-neuroligin-SHANK complex in human, mouse and rat and its relevance to autismShining a light on CNTNAP2: complex functions to complex disorders.Distribution of language-related Cntnap2 protein in neural circuits critical for vocal learningImaging-genetics in dyslexia: connecting risk genetic variants to brain neuroimaging and ultimately to reading impairments.What does CNTNAP2 reveal about autism spectrum disorder?Recent advances in the genetics of language impairmentGenes and vocal learningLanguage-related Cntnap2 gene is differentially expressed in sexually dimorphic song nuclei essential for vocal learning in songbirdsAbsence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits.Caspr and caspr2 are required for both radial and longitudinal organization of myelinated axons.Caspr2 autoantibodies target multiple epitopes.
P2860
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P2860
Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Caspr2, a new member of the ne ...... nd associates with K+ channels
@ast
Caspr2, a new member of the ne ...... nd associates with K+ channels
@en
Caspr2, a new member of the ne ...... nd associates with K+ channels
@en-gb
Caspr2, a new member of the ne ...... nd associates with K+ channels
@nl
type
label
Caspr2, a new member of the ne ...... nd associates with K+ channels
@ast
Caspr2, a new member of the ne ...... nd associates with K+ channels
@en
Caspr2, a new member of the ne ...... nd associates with K+ channels
@en-gb
Caspr2, a new member of the ne ...... nd associates with K+ channels
@nl
prefLabel
Caspr2, a new member of the ne ...... nd associates with K+ channels
@ast
Caspr2, a new member of the ne ...... nd associates with K+ channels
@en
Caspr2, a new member of the ne ...... nd associates with K+ channels
@en-gb
Caspr2, a new member of the ne ...... nd associates with K+ channels
@nl
P2093
P3181
P1433
P1476
Caspr2, a new member of the ne ...... nd associates with K+ channels
@en
P2093
J S Trimmer
R Martinez
S Einheber
P304
P3181
P356
10.1016/S0896-6273(00)81049-1
P407
P577
1999-12-01T00:00:00Z