Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6
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Epigenetic field defects in progression to cancerTumor-specific microsatellite instability: do distinct mechanisms underlie the MSI-L and EMAST phenotypes?MSH2/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sitesmiR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB RepairDNA replication fidelity and cancerStabilization of mismatch repair gene PMS2 by glycogen synthase kinase 3beta is implicated in the treatment of cervical carcinomaDefective mismatch repair, microsatellite mutation bias, and variability in clinical cancer phenotypesPMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance.A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.A genome-wide view of microsatellite instability: old stories of cancer mutations revisited with new sequencing technologiesDifferent roles of eukaryotic MutS and MutL complexes in repair of small insertion and deletion loops in yeast.The lower bound to the evolution of mutation rates.Evidence for mutation showers.AID-associated DNA repair pathways regulate malignant transformation in a murine model of BCL6-driven diffuse large B-cell lymphoma.Role of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations.Human postmeiotic segregation 2 exhibits biased repair at tetranucleotide microsatellite sequencesThe cellular, developmental and population-genetic determinants of mutation-rate evolutionDNA repair dysfunction in gastrointestinal tract cancers.Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation and homozygous truncating mutations.Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous PolyposisDNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice.Novel Implications in Molecular Diagnosis of Lynch Syndrome.Genomic instability and colon carcinogenesis: from the perspective of genes.Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.Progression inference for somatic mutations in cancer.Hypoxia and DNA repair.A triple-helix forming oligonucleotide targeting genomic DNA fails to induce mutation.Deficiency in DNA mismatch repair increases the rate of telomere shortening in normal human cells.
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P2860
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6
description
2006 nî lūn-bûn
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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
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name
Differing patterns of genetic ...... ms2, Mlh1, Msh2, Msh3 and Msh6
@ast
Differing patterns of genetic ...... ms2, Mlh1, Msh2, Msh3 and Msh6
@en
Differing patterns of genetic ...... ms2, Mlh1, Msh2, Msh3 and Msh6
@nl
type
label
Differing patterns of genetic ...... ms2, Mlh1, Msh2, Msh3 and Msh6
@ast
Differing patterns of genetic ...... ms2, Mlh1, Msh2, Msh3 and Msh6
@en
Differing patterns of genetic ...... ms2, Mlh1, Msh2, Msh3 and Msh6
@nl
prefLabel
Differing patterns of genetic ...... ms2, Mlh1, Msh2, Msh3 and Msh6
@ast
Differing patterns of genetic ...... ms2, Mlh1, Msh2, Msh3 and Msh6
@en
Differing patterns of genetic ...... ms2, Mlh1, Msh2, Msh3 and Msh6
@nl
P2093
P2860
P921
P3181
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P1476
Differing patterns of genetic ...... ms2, Mlh1, Msh2, Msh3 and Msh6
@en
P2093
Denise Campisi Hegan
Frank R Jirik
Latha Narayanan
Peter M Glazer
R Michael Liskay
Winfried Edelmann
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P304
P3181
P356
10.1093/CARCIN/BGL079
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P577
2006-12-01T00:00:00Z