Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein - sprookjes - yvandenbroek - TriplyDB

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

http://www.wikidata.org/entity/Q22251280

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Clinical immunologic approaches for the treatment of Alzheimer's disease Translatability scoring in drug development: eight case studies Current Insights into Molecular Mechanisms of Alzheimer Disease and Their Implications for Therapeutic Approaches Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation Binding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NAC Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice Reversal of long-term dendritic spine alterations in Alzheimer disease models Active and passive immunotherapy for neurodegenerative disorders P3 beta-amyloid peptide has a unique and potentially pathogenic immunohistochemical profile in Alzheimer's disease brain Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo Pin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism?The immunotherapy of Alzheimer's disease Synapses and Alzheimer's disease Targeting innate immunity for neurodegenerative disorders of the central nervous system Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds The amyloid hypothesis of Alzheimer's disease at 25 years Mouse Genetic Models of Human Brain Disorders Dissecting Alzheimer disease in Down syndrome using mouse models Engineering large animal models of human disease Alzheimer's in 3D culture: challenges and perspectives Behavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines.Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's disease The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception Ultrasound enhanced delivery of molecular imaging and therapeutic agents in Alzheimer's disease mouse models Small-animal PET imaging of amyloid-beta plaques with [11C]PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease Spines, plasticity, and cognition in Alzheimer's model mice On cognitive ecology and the environmental factors that promote Alzheimer disease: lessons from Octodon degus (Rodentia: Octodontidae)Insight of brain degenerative protein modifications in the pathology of neurodegeneration and dementia by proteomic profiling Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene Reelin and apoE actions on signal transduction, synaptic function and memory formation Deletion of the cathepsin B gene improves memory deficits in a transgenic ALZHeimer's disease mouse model expressing AβPP containing the wild-type β-secretase site sequence.Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity A mathematical model of the kinetics of beta-amyloid fibril growth from the denatured state Elevation of cystatin C in susceptible neurons in Alzheimer's disease Lead exposure increases levels of β-amyloid in the brain and CSF and inhibits LRP1 expression in APP transgenic mice Anti-Aβ drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer's disease

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

http://www.wikidata.org/entity/Q22251280

description

1995 nî lūn-bûn

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1995 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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1995 թվականի փետրվարին հրատարակված գիտական հոդված

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1995年の論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Alzheimer-type neuropathology ...... beta-amyloid precursor protein

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Alzheimer-type neuropathology ...... 7F β-amyloid precursor protein

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Ben Snyder

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Ben Wolozin

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Frances Gillespie

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Hua Tan

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523-527

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scholarly article

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1150073

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10.1038/373523A0

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6514

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373

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Eliezer Masliah

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278397957

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1010973433

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7845465

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Alzheimer's disease