Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
about
Rotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonismExplaining oscillations and variability in the p53-Mdm2 systemMain roads to melanomaThe RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complexParkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1Stabilization and activation of p53 by the coactivator protein TAFII31Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7Regulation of BOB.1/OBF.1 stability by SIAHThe tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulumAPC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complexMonoubiquitylation promotes mitochondrial p53 translocationTurning the RING domain protein MdmX into an active ubiquitin-protein ligaseThe deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2Critical role for Daxx in regulating Mdm2Regulation of p53 stability and function by the deubiquitinating enzyme USP42Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1TRIM11 binds to and destabilizes a key component of the activator-mediated cofactor complex (ARC105) through the ubiquitin-proteasome system{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligaseRING finger protein AO7 supports NF-kappaB-mediated transcription by interacting with the transactivation domain of the p65 subunitA novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF)The E3 ligase RNF8 regulates KU80 removal and NHEJ repairp53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitinationGNL3L depletion destabilizes MDM2 and induces p53-dependent G2/M arrestIdentification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domainsKaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 targets MDM2 to deregulate the p53 tumor suppressor pathwayMdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligaseRNF38 encodes a nuclear ubiquitin protein ligase that modifies p53p53 mediates the negative regulation of MDM2 by orphan receptor TR3The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complexAn essential function of the extreme C-terminus of MDM2 can be provided by MDMXATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damageMdmX is a substrate for the deubiquitinating enzyme USP2aMdm2 targets the p53 transcription cofactor JMY for degradationMutational analysis reveals a dual role of Mdm2 acidic domain in the regulation of p53 stabilityNARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)Comparative genomics and evolution of proteins involved in RNA metabolismMutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite
P2860
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P2860
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
description
2000 nî lūn-bûn
@nan
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@ast
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@en
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@en-gb
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@nl
type
label
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@ast
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@en
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@en-gb
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@nl
prefLabel
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@ast
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@en
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@en-gb
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@nl
P2093
P3181
P356
P1476
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
@en
P2093
A M Weissman
J P Jensen
K H Vousden
R L Ludwig
P304
P3181
P356
10.1074/JBC.275.12.8945
P407
P577
2000-03-24T00:00:00Z