A novel transcriptional repression domain mediates p21(WAF1/CIP1) induction of p300 transactivation
about
The histone acetyltransferase domains of CREB-binding protein (CBP) and p300/CBP-associated factor are not necessary for cooperativity with the class II transactivatorThe transcriptional activity of CITED1 is regulated by phosphorylation in a cell cycle-dependent mannerNegative regulation of cell growth and differentiation by TSG101 through association with p21(Cip1/WAF1).Modification with SUMO. A role in transcriptional regulationRegulation of RelA (p65) function by the large subunit of replication factor CA novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transductionRole of desumoylation in the development of prostate cancerThe p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitroNo germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancerInsights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF.The large subunit of replication factor C interacts with the histone deacetylase, HDAC1Effects of histone acetylation and DNA methylation on p21( WAF1) regulationNGF-dependent and tissue-specific transcription of vgf is regulated by a CREB-p300 and bHLH factor interactionCyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanismp21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal.SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activatorsp21-dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases.p21 in cancer: intricate networks and multiple activitiesGrainyhead-like 2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition.The role of p300 histone acetyltransferase in UV-induced histone modifications and MMP-1 gene transcriptionThe expression and functions of microRNAs in pancreatic adenocarcinoma and hepatocellular carcinomaTumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer.Human immunodeficiency virus type 1-induced macrophage gene expression includes the p21 gene, a target for viral regulation.A novel function for p21Cip1 and acetyltransferase p/CAF as critical transcriptional regulators of TGFβ-mediated breast cancer cell migration and invasion.p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation.Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agentp21 as a transcriptional co-repressor of S-phase and mitotic control genesDifferential regulation of c-Jun-dependent transcription by SUMO-specific proteases.Doxorubicin Activates Hepatitis B Virus Replication by Elevation of p21 (Waf1/Cip1) and C/EBPα Expression.The p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO.Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130.Histone deacetylases as transcriptional activators? Role reversal in inducible gene regulation.A Systems Biology Approach to Characterize Biomarkers for Blood Stasis Syndrome of Unstable Angina Patients by Integrating MicroRNA and Messenger RNA Expression ProfilingCorepressive action of CBP on androgen receptor transactivation in pericentric heterochromatin in a Drosophila experimental model system.Mechanical regulation of the proangiogenic factor CCN1/CYR61 gene requires the combined activities of MRTF-A and CREB-binding protein histone acetyltransferase.A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster.Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cellsRegulation of inducible nitric oxide synthase expression by viral A238L-mediated inhibition of p65/RelA acetylation and p300 transactivation.Escape from p21-mediated oncogene-induced senescence leads to cell dedifferentiation and dependence on anti-apoptotic Bcl-xL and MCL1 proteins.Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence.
P2860
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P2860
A novel transcriptional repression domain mediates p21(WAF1/CIP1) induction of p300 transactivation
description
2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
A novel transcriptional repres ...... uction of p300 transactivation
@ast
A novel transcriptional repres ...... uction of p300 transactivation
@en
A novel transcriptional repres ...... uction of p300 transactivation
@en-gb
A novel transcriptional repres ...... uction of p300 transactivation
@nl
type
label
A novel transcriptional repres ...... uction of p300 transactivation
@ast
A novel transcriptional repres ...... uction of p300 transactivation
@en
A novel transcriptional repres ...... uction of p300 transactivation
@en-gb
A novel transcriptional repres ...... uction of p300 transactivation
@nl
prefLabel
A novel transcriptional repres ...... uction of p300 transactivation
@ast
A novel transcriptional repres ...... uction of p300 transactivation
@en
A novel transcriptional repres ...... uction of p300 transactivation
@en-gb
A novel transcriptional repres ...... uction of p300 transactivation
@nl
P2093
P2860
P3181
P1476
A novel transcriptional repres ...... uction of p300 transactivation
@en
P2093
A W Snowden
G A Webster
L A Anderson
N D Perkins
P2860
P304
P3181
P356
10.1128/MCB.20.8.2676-2686.2000
P407
P577
2000-04-01T00:00:00Z