Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle
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The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activationThe pan-chemokine inhibitor NR58-3.14.3 abolishes tumour necrosis factor-alpha accumulation and leucocyte recruitment induced by lipopolysaccharide in vivoStructure modeling of all identified G protein-coupled receptors in the human genomeStructural insights from binding poses of CCR2 and CCR5 with clinically important antagonists: a combined in silico studyCCL2 promotes P2X4 receptor trafficking to the cell surface of microgliaThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsDefective TGF-β signaling in bone marrow-derived cells prevents hedgehog-induced skin tumors.Inhibition of the angiogenesis by the MCP-1 (monocyte chemoattractant protein-1) binding peptide.HIV-1 clade B Tat, but not clade C Tat, increases X4 HIV-1 entry into resting but not activated CD4+ T cells.First pharmacophore model of CCR3 receptor antagonists and its homology model-assisted, stepwise virtual screening.An antimicrobial peptide regulates tumor-associated macrophage trafficking via the chemokine receptor CCR2, a model for tumorigenesis.Defining the chemokine basis for leukocyte recruitment during viral encephalitis.Structure modeling of the chemokine receptor CCR5: implications for ligand binding and selectivity.MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium.New therapeutics that modulate chemokine networks.Targeting monocyte chemoattractant protein-1 signalling in disease.G protein-coupled receptors--recent advancesBlockade of CCR2 ameliorates progressive fibrosis in kidney.Potential new drugs for therapy of chronic obstructive pulmonary disease.D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestionLymphocyte trafficking to inflamed skin--molecular mechanisms and implications for therapeutic target molecules.Molecular requirements for inhibition of the chemokine receptor CCR8--probe-dependent allosteric interactions.Monocyte chemoattractant protein-1 affects migration of hippocampal neural progenitors following status epilepticus in rats.Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension.The monocyte chemoattractant protein-1/CCR2 loop, inducible by TGF-beta, increases podocyte motility and albumin permeability.Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes.Chemokine receptor antagonists: Part 1.CCR3 antagonists: a survey of the patent literature.Novel C-C chemokine receptor 2 antagonists in metabolic disease: a review of recent developments.Pharmacological modulation of chemokine receptor function.Rational design of CCR2 antagonists: a survey of computational studies.Progress in the discovery of CC chemokine receptor 2 antagonists, 2009 - 2012.Chemokine receptors as important regulators of pathogenesis during arboviral encephalitisDissecting fibrosis: therapeutic insights from the small-molecule toolbox.Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach.Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5).The RS504393 Influences the Level of Nociceptive Factors and Enhances Opioid Analgesic Potency in Neuropathic Rats.Involvement of spinal chemokine CCL2 in the hyperalgesia evoked by bone cancer in mice: a role for astroglia and microglia.Role of the C-C chemokine receptor-2 in a murine model of injury-induced osteoarthritis.Suppression of vaccine immunity by inflammatory monocytes.
P2860
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P2860
Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Identification of the binding ...... otif within the helical bundle
@ast
Identification of the binding ...... otif within the helical bundle
@en
Identification of the binding ...... otif within the helical bundle
@en-gb
Identification of the binding ...... otif within the helical bundle
@nl
type
label
Identification of the binding ...... otif within the helical bundle
@ast
Identification of the binding ...... otif within the helical bundle
@en
Identification of the binding ...... otif within the helical bundle
@en-gb
Identification of the binding ...... otif within the helical bundle
@nl
prefLabel
Identification of the binding ...... otif within the helical bundle
@ast
Identification of the binding ...... otif within the helical bundle
@en
Identification of the binding ...... otif within the helical bundle
@en-gb
Identification of the binding ...... otif within the helical bundle
@nl
P2093
P2860
P921
P356
P1476
Identification of the binding ...... otif within the helical bundle
@en
P2093
D McCarley
G S Weatherhead
J Dankwardt
J M Lapierre
K Jarnagin
P2860
P304
P356
10.1074/JBC.M000692200
P407
P577
2000-08-18T00:00:00Z