Identification of the human cytochrome P450, P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans-retinoic acid metabolism
about
Genetic variants in meiotic program initiation pathway genes are associated with spermatogenic impairment in a Han Chinese populationPhenotypic and functional consequences of haploinsufficiency of genes from exocyst and retinoic acid pathway due to a recurrent microdeletion of 2p13.2A novel human cytochrome P450, CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acidIdentification of all-trans-retinol:all-trans-13,14-dihydroretinol saturaseTranscriptional co-operativity between distant retinoic acid response elements in regulation of Cyp26A1 inducibilityThe discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression systemSignaling through retinoic acid receptors in cardiac development: Doing the right things at the right timesLeukocyte homing, fate, and function are controlled by retinoic acidRegulation of entry into gametogenesisLong-distance retinoid signaling in the zebra finch brainIdentification of Tazarotenic Acid as the First Xenobiotic Substrate of Human Retinoic Acid Hydroxylase CYP26A1 and CYP26B1Association of multiple developmental defects and embryonic lethality with loss of microsomal NADPH-cytochrome P450 oxidoreductaseRegulation of a highly specific retinoic acid-4-hydroxylase (CYP26A1) enzyme and all-trans-retinoic acid metabolism in human intestinal, liver, endothelial, and acute promyelocytic leukemia cellsThe retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures.Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear.Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongationDownstream genes of Pax6 revealed by comprehensive transcriptome profiling in the developing rat hindbrainRetinyl ester formation by lecithin: retinol acyltransferase is a key regulator of retinoid homeostasis in mouse embryogenesisApplication of synthetic photostable retinoids induces novel limb and facial phenotypes during chick embryogenesis in vivoBMP and retinoic acid regulate anterior-posterior patterning of the non-axial mesoderm across the dorsal-ventral axis.A transcriptomic approach to elucidate the physiological significance of human cytochrome P450 2S1 in bronchial epithelial cellsSummary of information on human CYP enzymes: human P450 metabolism data.A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation.Inhibition of retinoic acid biosynthesis by the bisdichloroacetyldiamine WIN 18,446 markedly suppresses spermatogenesis and alters retinoid metabolism in mice.Expression and functional characterization of cytochrome P450 26A1, a retinoic acid hydroxylaseCyp26b1 regulates retinoic acid-dependent signals in T cells and its expression is inhibited by transforming growth factor-β.Quantification of endogenous retinoids.The relative importance of CYP26A1 in hepatic clearance of all-trans retinoic acid.Cloning and functional studies of a splice variant of CYP26B1 expressed in vascular cellsFocal facial dermal dysplasia, type IV, is caused by mutations in CYP26C1Metabolism and transactivation activity of 13,14-dihydroretinoic acid.Therapeutic potential of the inhibition of the retinoic acid hydroxylases CYP26A1 and CYP26B1 by xenobiotics.Microarray assessment of the influence of the conceptus on gene expression in the mouse uterus during decidualization.Evidence for defective retinoid transport and function in late onset Alzheimer's diseasePolymorphism in the retinoic acid metabolizing enzyme CYP26B1 and the development of Crohn's Disease.Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoidsComparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylasesVitamin A in reproduction and developmentXenobiotic-metabolizing cytochromes P450 in ontogeny: evolving perspective.A CYP26B1 polymorphism enhances retinoic acid catabolism and may aggravate atherosclerosis.
P2860
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P2860
Identification of the human cytochrome P450, P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans-retinoic acid metabolism
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Identification of the human cy ...... trans-retinoic acid metabolism
@ast
Identification of the human cy ...... trans-retinoic acid metabolism
@en
Identification of the human cy ...... trans-retinoic acid metabolism
@en-gb
Identification of the human cy ...... trans-retinoic acid metabolism
@nl
type
label
Identification of the human cy ...... trans-retinoic acid metabolism
@ast
Identification of the human cy ...... trans-retinoic acid metabolism
@en
Identification of the human cy ...... trans-retinoic acid metabolism
@en-gb
Identification of the human cy ...... trans-retinoic acid metabolism
@nl
prefLabel
Identification of the human cy ...... trans-retinoic acid metabolism
@ast
Identification of the human cy ...... trans-retinoic acid metabolism
@en
Identification of the human cy ...... trans-retinoic acid metabolism
@en-gb
Identification of the human cy ...... trans-retinoic acid metabolism
@nl
P2093
P2860
P921
P3181
P356
P1476
Identification of the human cy ...... trans-retinoic acid metabolism
@en
P2093
M Petkovich
S Creighton
S Everingham
P2860
P304
P3181
P356
10.1073/PNAS.120161397
P407
P577
2000-06-06T00:00:00Z