Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
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GJC2 missense mutations cause human lymphedemaMutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndromeProtein tyrosine phosphatase PTPN14 is a regulator of lymphatic function and choanal development in humansMutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasiaBiomedicine and diseases: the Klippel-Trenaunay syndrome, vascular anomalies and vascular morphogenesisLymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factorThe lymphangiogenic vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1Role of hypoxia and vascular endothelial growth factors in lymphangiogenesisLymphangiogenesis and Lesion Heterogeneity in Interstitial Lung DiseasesOedema, solid organ transplantation and mammalian target of rapamycin inhibitor/proliferation signal inhibitors (mTOR-I/PSIs)Development of the mammalian lymphatic vasculatureReceptor tyrosine kinase-mediated angiogenesisVascular anomalies: from genetics toward models for therapeutic trialsEvidence for SH2 domain-containing 5'-inositol phosphatase-2 (SHIP2) contributing to a lymphatic dysfunctionEPHB4 kinase-inactivating mutations cause autosomal dominant lymphatic-related hydrops fetalis.A Molecular Brake in the Kinase Hinge Region Regulates the Activity of Receptor Tyrosine KinasesStructural and mechanistic insights into VEGF receptor 3 ligand binding and activationA model for gene therapy of human hereditary lymphedemaVascular endothelial growth factor D is dispensable for development of the lymphatic system.Genetic background of HSH in three Polish families and a patient with an X;9 translocationNF-kappaB-related genetic diseasesGenetics of lymphatic anomaliesAtypical forms of incontinentia pigmenti in male individuals result from mutations of a cytosine tract in exon 10 of NEMO (IKK-gamma)Dosage-dependent requirement for mouse Vezf1 in vascular system developmentAn essential role for Prox1 in the induction of the lymphatic endothelial cell phenotypeCharacterization of indolinones which preferentially inhibit VEGF-C- and VEGF-D-induced activation of VEGFR-3 rather than VEGFR-2Tbx1 regulates Vegfr3 and is required for lymphatic vessel developmentHigh-resolution 3D volumetry versus conventional measuring techniques for the assessment of experimental lymphedema in the mouse hindlimb.Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades.Lymphatic vessel density and function in experimental bladder cancer.A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development.E2F1 promotes angiogenesis through the VEGF-C/VEGFR-3 axis in a feedback loop for cooperative induction of PDGF-B.lyve1 expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafish.Characterization of pathogenic germline mutations in human protein kinases.Expression of a flt-4 (VEGFR3) splicing variant in primary human prostate tumors. VEGF D and flt-4t(Delta773-1081) overexpression is diagnostic for sentinel lymph node metastasis.Elevated expression of VEGFR-3 in lymphatic endothelial cells from lymphangiomasProliferating mesodermal cells in murine embryos exhibiting macrophage and lymphendothelial characteristicsNeostatin-7 regulates bFGF-induced corneal lymphangiogenesisMYC high level gene amplification is a distinctive feature of angiosarcomas after irradiation or chronic lymphedemaDermal collagen and lipid deposition correlate with tissue swelling and hydraulic conductivity in murine primary lymphedema.
P2860
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P2860
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@ast
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@en
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@en-gb
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@nl
type
label
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@ast
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@en
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@en-gb
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@nl
prefLabel
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@ast
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@en
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@en-gb
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@nl
P2093
P3181
P356
P1433
P1476
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
@en
P2093
Ferrell RE
Karkkainen MJ
Lawrence EC
Levinson KL
McTigue MA
P2888
P304
P3181
P356
10.1038/75997
P407
P577
2000-06-01T00:00:00Z
P5875
P6179
1031637972