Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration
about
Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulationAssociation of Grb7 with phosphoinositides and its role in the regulation of cell migrationThe adaptor Grb7 is a novel calmodulin-binding protein: functional implications of the interaction of calmodulin with Grb7EphB1 associates with Grb7 and regulates cell migrationRegulation of focal adhesion kinase by a novel protein inhibitor FIP200R-Ras promotes focal adhesion formation through focal adhesion kinase and p130(Cas) by a novel mechanism that differs from integrins.Candidate genes for testicular cancer evaluated by in situ protein expression analyses on tissue microarraysThe Regulation of Cellular Responses to Mechanical Cues by Rho GTPasesGrb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferationFocal adhesion kinase regulation of N-WASP subcellular localization and functionThe Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functionsAltered expression and deletion of RMO1 in osteosarcomaComparative study of protein tyrosine phosphatase-epsilon isoforms: membrane localization confers specificity in cellular signallingThe PIR domain of Grb14 is an intrinsically unstructured protein: implication in insulin signalingKnock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7.Coamplification and coexpression of GRB7 and ERBB2 is found in high grade intraepithelial neoplasia and in invasive Barrett's carcinoma.In situ photoactivation of a caged phosphotyrosine peptide derived from focal adhesion kinase temporarily halts lamellar extension of single migrating tumor cells.Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repressionGrowth factor receptor-bound protein-7 (Grb7) as a prognostic marker and therapeutic target in breast cancer.Integrin signaling through FAK in the regulation of mammary stem cells and breast cancerFocal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasisGrb7 and Filamin-a associate and are colocalized to cell membrane ruffles upon EGF stimulation.Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14.EGF-induced Grb7 recruits and promotes Ras activity essential for the tumorigenicity of Sk-Br3 breast cancer cells.Preparation and crystallization of the Grb7 SH2 domain in complex with the G7-18NATE nonphosphorylated cyclic inhibitor peptide.The cell migration protein Grb7 associates with transcriptional regulator FHL2 in a Grb7 phosphorylation-dependent manner.Focal adhesion kinase as a potential target in oncology.Identification of FAK substrate peptides via colorimetric screening of a one-bead one-peptide combinatorial library.The adaptor Grb7 links netrin-1 signaling to regulation of mRNA translation.Grb10 and Grb14: enigmatic regulators of insulin action--and more?Grb7 Protein Stability Modulated by Pin1 in Association with Cell Cycle ProgressionAdapter protein connections: the MRL and Grb7 protein families.ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix.Loss of the Rap1 effector RIAM results in leukocyte adhesion deficiency due to impaired β2 integrin function in miceBackbone nuclear relaxation characteristics and calorimetric investigation of the human Grb7-SH2/erbB2 peptide complexFunction of focal adhesion kinase scaffolding to mediate endophilin A2 phosphorylation promotes epithelial-mesenchymal transition and mammary cancer stem cell activities in vivoDissecting GRB7-mediated signals for proliferation and migration in HER2 overexpressing breast tumor cells: GTP-ase rules.Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
P2860
Q24291017-93601A1E-021E-4C0F-8074-F26D4FDB6C15Q24293300-017F9CC3-EC52-45C2-9050-4761B9228F6CQ24297860-683B66A4-4B51-4F08-A70C-F3ADEC9D093CQ24299497-90608B85-7CD1-4D5C-9C16-921173E511A1Q24306491-5B94E6A3-5072-4F2A-A9CE-56CC3E7FC3D8Q24530047-789FB38A-BD03-4FC0-BEA3-F33A90922CB2Q24540799-77D12378-21B4-4ECE-B707-7650BFDC65C1Q24550972-CDCD51EC-6434-4C45-845D-9A697496ADA0Q26750608-62F0AB1C-3899-4376-AF10-742F496477D3Q27648499-CAA55406-6AB6-46CC-966C-DC4726D90801Q28118737-4A0DF90C-9640-4A91-B286-42D0C122DE2DQ28199355-8EDD11AD-9EDB-4A0C-84CC-AE76D95208B5Q28299137-1690D443-1B2F-4B8F-9BD5-7C1B0D00CFB6Q28359634-BEDF2E0D-7400-4297-B530-86683D57472BQ28909797-29EDC405-363B-4C40-8410-750AAE2A1D56Q30495320-0B77D20C-F3FF-456D-AE18-24569485E2F8Q31036345-D40A6910-1A11-45AD-9FE7-F507B2BE4EA3Q31114947-2A9CE7B5-00B7-4EFB-B2AE-C4BDADEA808AQ31158529-A348E0EC-C0A1-472E-808C-6EA79B66D8BEQ33528957-21275C6A-8F46-4379-98C6-00D189506E66Q33676758-9396DCBF-49E4-476C-85B8-78E2E9D8281AQ33766299-E926C6ED-179E-4A6B-BCA5-5FEFAA3BED51Q33789414-82265739-43CE-400E-AD45-68154F240150Q33895854-F6975051-6B18-4431-BD29-F7B66509302EQ34103542-9547673F-4D25-41D9-BDB0-EBCC391D6A6DQ34121550-57F05656-5FDD-4856-80CB-3E1E80E95D24Q34387280-917AFC4F-96BE-4CE5-9F49-9D6961DBAA4CQ34692283-8D2D7741-AA88-4060-9253-12868C8E3D0FQ35058125-65DC5490-3CC7-493F-9C93-D0D31AFDE977Q35569727-C821C7C7-E5D3-40DA-94A1-1F560B8CCE15Q35691334-59784ECA-880B-455F-8845-7CE50962D4BFQ36131371-A8CDD81C-37D0-4144-ADEE-E5BC021C8D70Q36141267-7A1EDA87-C90F-432B-B933-D13B9FEDE2E1Q36294476-DB30BC9C-A70C-4DA4-867A-68C4F43C1057Q36324827-F0EB82FD-CCFB-4791-ADF6-57F56C52C129Q36382181-C91D4970-5282-437F-8CFF-A34CD7817C74Q36476851-4C04639F-ACCC-4885-84EB-C28662F4F139Q36579538-7B8BA67D-CFA3-4AE5-BBF0-CA133A413601Q36758884-3F818B8F-B476-4D72-9EC3-E25A9111A0FAQ36964946-D1B39DFB-C9E8-4327-BB8A-A60FEC6E875B
P2860
Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Role of Grb7 targeting to foca ...... n regulation of cell migration
@ast
Role of Grb7 targeting to foca ...... n regulation of cell migration
@en
Role of Grb7 targeting to foca ...... n regulation of cell migration
@en-gb
Role of Grb7 targeting to foca ...... n regulation of cell migration
@nl
type
label
Role of Grb7 targeting to foca ...... n regulation of cell migration
@ast
Role of Grb7 targeting to foca ...... n regulation of cell migration
@en
Role of Grb7 targeting to foca ...... n regulation of cell migration
@en-gb
Role of Grb7 targeting to foca ...... n regulation of cell migration
@nl
prefLabel
Role of Grb7 targeting to foca ...... n regulation of cell migration
@ast
Role of Grb7 targeting to foca ...... n regulation of cell migration
@en
Role of Grb7 targeting to foca ...... n regulation of cell migration
@en-gb
Role of Grb7 targeting to foca ...... n regulation of cell migration
@nl
P2093
P2860
P921
P3181
P356
P1476
Role of Grb7 targeting to foca ...... n regulation of cell migration
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M001997200
P407
P577
2000-09-15T00:00:00Z