Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinantTB: the Yin and Yang of lipid mediatorsLeptospira interrogans stably infects zebrafish embryos, altering phagocyte behavior and homing to specific tissuesThe lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humansPseudomonas aeruginosa Type III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryosThe role of the granuloma in expansion and dissemination of early tuberculous infection.Tumor necrosis factor signaling mediates resistance to mycobacteria by inhibiting bacterial growth and macrophage death.Why is long-term therapy required to cure tuberculosis?Do mycobacteria produce endospores?Verapamil, and its metabolite norverapamil, inhibit macrophage-induced, bacterial efflux pump-mediated tolerance to multiple anti-tubercular drugs.Complex pattern of Mycobacterium marinum gene expression during long-term granulomatous infection.Looking within the zebrafish to understand the tuberculous granuloma.The zebrafish guide to tuberculosis immunity and treatment.Insights into early mycobacterial pathogenesis from the zebrafish.Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.Dichotomous role of the macrophage in early Mycobacterium marinum infection of the zebrafishDrug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism.Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium.Mycobacterium marinum infection of adult zebrafish causes caseating granulomatous tuberculosis and is moderated by adaptive immunity.The secret lives of the pathogenic mycobacteria.New models for the study of Mycobacterium-host interactions.Neutrophils exert protection in the early tuberculous granuloma by oxidative killing of mycobacteria phagocytosed from infected macrophagesComparative pathogenesis of Mycobacterium marinum and Mycobacterium tuberculosis.Trafficking of superinfecting Mycobacterium organisms into established granulomas occurs in mammals and is independent of the Erp and ESX-1 mycobacterial virulence loci.Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In VivoAntimicrobial efflux pumps and Mycobacterium tuberculosis drug tolerance: evolutionary considerations.Revisiting the role of the granuloma in tuberculosis.Immunity and Immunopathology in the Tuberculous GranulomaHost evasion and exploitation schemes of Mycobacterium tuberculosis.Leukotriene A4 Hydrolase Genotype and HIV Infection Influence Intracerebral Inflammation and Survival From Tuberculous Meningitis.A Macrophage Response to Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage in Leprosy."The Impact of Mycobacterium tuberculosis Immune Evasion on Protective Immunity: Implications for TB Vaccine Design" - Meeting report.Mycobacterial ESX-1 secretion system mediates host cell lysis through bacterium contact-dependent gross membrane disruptions.Insights into tuberculosis from the zebrafish model.An in vivo platform for rapid high-throughput antitubercular drug discovery.TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species.An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection.Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections.Mycobacterium marinum Erp is a virulence determinant required for cell wall integrity and intracellular survival.Spotlight on zebrafish: translational impact.
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