Up-regulation of HLA class-I antigen expression and antigen-specific CTL response in cervical cancer cells by the demethylating agent hydralazine and the histone deacetylase inhibitor valproic acid
about
Tumor hypomethylation at 6p21.3 associates with longer time to recurrence of high-grade serous epithelial ovarian cancerA potential role for immunotherapy in thyroid cancer by enhancing NY-ESO-1 cancer antigen expressionA double-blind, placebo-controlled, randomized phase III trial of chemotherapy plus epigenetic therapy with hydralazine valproate for advanced cervical cancer. Preliminary results.Histone deacetylase regulation of immune gene expression in tumor cells.Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cellsRole of gene methylation in antitumor immune response: implication for tumor progression.In vitro evidence of the presence of mesenchymal stromal cells in cervical cancer and their role in protecting cancer cells from cytotoxic T cell activity.Targeting of histone deacetylases to reactivate tumour suppressor genes and its therapeutic potential in a human cervical cancer xenograft model.Mesenchymal stromal cells derived from cervical cancer produce high amounts of adenosine to suppress cytotoxic T lymphocyte functions.Epigenetics in cancer stem cells.Emerging drugs for cervical cancer.Hydralazine-valproate: a repositioned drug combination for the epigenetic therapy of cancer.Emerging drugs for the treatment of cervical cancer.Epigenetic therapy for solid tumors: from bench science to clinical trials.Enhanced antitumor efficacy of telomerase-specific oncolytic adenovirus with valproic acid against human cancer cells.Methylation-specific ligation detection reaction (msLDR): a new approach for multiplex evaluation of methylation patterns.Analysis of Class I Major Histocompatibility Complex Gene Transcription in Human Tumors Caused by Human Papillomavirus Infection.5-aza-2'-deoxycytidine (DAC) treatment downregulates the HPV E6 and E7 oncogene expression and blocks neoplastic growth of HPV-associated cancer cells.The antihypertensive drug hydralazine activates the intrinsic pathway of apoptosis and causes DNA damage in leukemic T cells.Identification of key amino acid residues that determine the ability of high risk HPV16-E7 to dysregulate major histocompatibility complex class I expression.Protein methyltransferases and demethylases dictate CD8+ T-cell exclusion in squamous cell carcinoma of the head and neck.Efficacy of hydralazine and valproate in cutaneous T-cell lymphoma, a phase II study.Exploration of the valproic acid binding site on histone deacetylase 8 using docking and molecular dynamic simulations.
P2860
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P2860
Up-regulation of HLA class-I antigen expression and antigen-specific CTL response in cervical cancer cells by the demethylating agent hydralazine and the histone deacetylase inhibitor valproic acid
description
2006 nî lūn-bûn
@nan
2006 թուականին հրատարակուած գիտական յօդուած
@hyw
2006 թվականին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@ast
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@en
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@en-gb
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@nl
type
label
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@ast
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@en
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@en-gb
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@nl
prefLabel
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@ast
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@en
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@en-gb
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@nl
P2093
P2860
P50
P3181
P356
P1476
Up-regulation of HLA class-I a ...... tylase inhibitor valproic acid
@en
P2093
Alfonso Duenas-González
Benny Weiss-Steider
David Cantú
Edelmiro Santiago-Osorio
Enrique Pérez-Cárdenas
Erick De la Cruz-Hernández
Jorge Hernández-Montes
Marcela Lizano-Soberón
Martha Patricia Rojo-Aguilar
Víctor Hugo Rosales
P2860
P2888
P3181
P356
10.1186/1479-5876-4-55
P407
P577
2006-12-27T00:00:00Z
P5875
P6179
1032934033