Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells
about
An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cellsSignaling in Effector Lymphocytes: Insights toward Safer ImmunotherapyCell biological steps and checkpoints in accessing NK cell cytotoxicityRemodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopyAssociation of the X-linked lymphoproliferative disease gene product SAP/SH2D1A with 2B4, a natural killer cell-activating molecule, is dependent on phosphoinositide 3-kinaseDeficiency of small GTPase Rac2 affects T cell activationNatural killer cell differentiation driven by Tyro3 receptor tyrosine kinasesDeficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations.Rapid activation receptor- or IL-2-induced lytic granule convergence in human natural killer cells requires Src, but not downstream signalingGenome wide transcriptional analysis of resting and IL2 activated human natural killer cells: gene expression signatures indicative of novel molecular signaling pathways.The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphomaDirect TLR2 signaling is critical for NK cell activation and function in response to vaccinia viral infection.SWAP-70-like adapter of T cells: a novel Lck-regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+ signaling in T cellsSphingosine kinase-1 is required for toll mediated beta-defensin 2 induction in human oral keratinocytes.Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation.Effects of novel isoform-selective phosphoinositide 3-kinase inhibitors on natural killer cell function.Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligaseToll-like receptor-mediated production of IL-1Ra is negatively regulated by GSK3 via the MAPK ERK1/2.A Two-Phase Expansion Protocol Combining Interleukin (IL)-15 and IL-21 Improves Natural Killer Cell Proliferation and Cytotoxicity against RhabdomyosarcomaIL-21-mediated reversal of NK cell exhaustion facilitates anti-tumour immunity in MHC class I-deficient tumoursLysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling.Suppression of natural killer cell cytotoxicity in postpartum women.Role of protein kinase C in TBT-induced inhibition of lytic function and MAPK activation in human natural killer cells.On guard--activating NK cell receptors.Mifepristone increases the cytotoxicity of uterine natural killer cells by acting as a glucocorticoid antagonist via ERK activationTyrosine kinase pathways modulate tumor susceptibility to natural killer cellsCombination of temsirolimus (CCI-779) with chemoradiation in newly diagnosed glioblastoma multiforme (GBM) (NCCTG trial N027D) is associated with increased infectious risksRas-related C3 Botulinum Toxin Substrate (Rac) and Src Family Kinases (SFK) Are Proximal and Essential for Phosphatidylinositol 3-Kinase (PI3K) Activation in Natural Killer (NK) Cell-mediated Direct Cytotoxicity against Cryptococcus neoformans.PAK1 mediates resistance to PI3K inhibition in lymphomas.Selective role of mevalonate pathway in regulating perforin but not FasL and TNFalpha release in human Natural Killer cellsUnderstanding Rho/Rac biology in T-cells using animal models.CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cellsNatural killer cell activation in mice and men: different triggers for similar weapons?Emerging functions of p21-activated kinases in human cancer cells.Visualization of signaling pathways and cortical cytoskeleton in cytolytic and noncytolytic natural killer cell immune synapses.The innate immune response to tumors and its role in the induction of T-cell immunity.PTEN is a negative regulator of NK cell cytolytic function.Regulation of lymphocyte-mediated killing by GTP-binding proteins.PTEN regulates natural killer cell trafficking in vivoA genome-wide association study in catfish reveals the presence of functional hubs of related genes within QTLs for columnaris disease resistance.
P2860
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P2860
Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells
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2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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Pivotal role of phosphoinositi ...... xicity in natural killer cells
@ast
Pivotal role of phosphoinositi ...... xicity in natural killer cells
@en
Pivotal role of phosphoinositi ...... xicity in natural killer cells
@nl
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label
Pivotal role of phosphoinositi ...... xicity in natural killer cells
@ast
Pivotal role of phosphoinositi ...... xicity in natural killer cells
@en
Pivotal role of phosphoinositi ...... xicity in natural killer cells
@nl
prefLabel
Pivotal role of phosphoinositi ...... xicity in natural killer cells
@ast
Pivotal role of phosphoinositi ...... xicity in natural killer cells
@en
Pivotal role of phosphoinositi ...... xicity in natural killer cells
@nl
P2093
P921
P3181
P356
P1433
P1476
Pivotal role of phosphoinositi ...... xicity in natural killer cells
@en
P2093
B C Corliss
D L Gilvary
E Hong-Geller
P304
P3181
P356
10.1038/80859
P407
P577
2000-11-01T00:00:00Z