Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
about
The gene for interleukin-21 receptor is the partner of BCL6 in t(3;16)(q27;p11), which is recurrently observed in diffuse large B-cell lymphomaInterleukin-21 activates human natural killer cells and modulates their surface receptor expressionIl-21 enhances NK cell activation and cytolytic activity and induces Th17 cell differentiation in inflammatory bowel diseaseBiology of IL-21 and the IL-21 receptorCloning and characterization of an isoform of interleukin-21Interleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity.NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expressionFollicular helper T cells in immunity and systemic autoimmunityThe biological functions of T helper 17 cell effector cytokines in inflammationInterleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllersFollicular helper T cells: lineage and locationInterleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cellsCloning of a type I cytokine receptor most related to the IL-2 receptor beta chainInterleukin-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responsesDifferential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV)Cloning and characterization of deer mouse (Peromyscus maniculatus) cytokine and chemokine cDNAsSequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer.A brief history of T cell help to B cellsThe role of interleukin-21 in HIV infectionThe plasmacytoid dendritic cell as the Swiss army knife of the immune system: molecular regulation of its multifaceted functionsMembrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cellsInterleukin-21 enhances rituximab activity in a cynomolgus monkey model of B cell depletion and in mouse B cell lymphoma modelsMaintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21The existence of multiple conformers of interleukin-21 directs engineering of a superpotent analogueAutologous Graft-versus-Tumor Effect: Reality or Fiction?The Biological Effects of IL-21 Signaling on B-Cell-Mediated Responses in Organ TransplantationIL-21: roles in immunopathology and cancer therapyInterleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiationIL-21 enhances NK cell functions and survival in healthy and HIV-infected patients with minimal stimulation of viral replicationMycobacterium tuberculosis-Specific IL-21+IFN-γ+CD4+ T Cells Are Regulated by IL-12A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunityAntigen-specific monoclonal antibodies isolated from B cells expressing constitutively active STAT5Advances of the interleukin-21 signaling pathway in immunity and angiogenesis.Assessment of sequence homology and immunologic cross-reactivity between tree shrew (Tupaia belangeri) and human IL-21.IL-21 promotes late activator APC-mediated T follicular helper cell differentiation in experimental pulmonary virus infection.IL-21 mediated Foxp3 suppression leads to enhanced generation of antigen-specific CD8+ cytotoxic T lymphocytes.FcγRIIIa-Syk Co-signal Modulates CD4+ T-cell Response and Up-regulates Toll-like Receptor (TLR) ExpressionExpression pattern of serum cytokines in hepatitis B virus infected patients with persistently normal alanine aminotransferase levels.IL-21 limits peripheral lymphocyte numbers through T cell homeostatic mechanismsA phase I study of recombinant human interleukin-21 (rIL-21) in combination with sunitinib in patients with metastatic renal cell carcinoma (RCC).
P2860
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P2860
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
description
2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@ast
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@en
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@en-gb
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@nl
type
label
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@ast
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@en
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@en-gb
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@nl
prefLabel
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@ast
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@en
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@en-gb
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@nl
P2093
P921
P3181
P356
P1433
P1476
Interleukin 21 and its recepto ...... ulation of lymphocyte function
@en
P2093
C Lofton-Day
C Sprecher
P2888
P3181
P356
10.1038/35040504
P407
P577
2000-11-02T00:00:00Z
P5875
P6179
1027439653