WBSCR14, a gene mapping to the Williams--Beuren syndrome deleted region, is a new member of the Mlx transcription factor network
about
Submicroscopic deletion in patients with Williams-Beuren syndrome influences expression levels of the nonhemizygous flanking genesMondoA-Mlx heterodimers are candidate sensors of cellular energy status: mitochondrial localization and direct regulation of glycolysisThe subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3A novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex.Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligaseFunctional interactions among members of the MAX and MLX transcriptional network during oncogenesisUsing transcription modules to identify expression clusters perturbed in Williams-Beuren syndromec-Myc is required for the glucose-mediated induction of metabolic enzyme genesNeural mechanisms in Williams syndrome: a unique window to genetic influences on cognition and behaviour.Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells.Adenosine-containing molecules amplify glucose signaling and enhance txnip expression.c-Myc is required for the CHREBP-dependent activation of glucose-responsive genes.Glucose and cAMP: adversaries in the regulation of hepatic gene expressionIntegrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression.A novel N-terminal domain may dictate the glucose response of Mondo proteins.An atypical 7q11.23 deletion in a normal IQ Williams-Beuren syndrome patient.ChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cellsNew perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c.ChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cells.Association between CETP, MLXIPL, and TOMM40 polymorphisms and serum lipid levels in a Latvian population.Importin-alpha protein binding to a nuclear localization signal of carbohydrate response element-binding protein (ChREBP).Williams-Beuren syndrome: a challenge for genotype-phenotype correlations.Evolution of the Max and Mlx networks in animals.A critical role for the loop region of the basic helix-loop-helix/leucine zipper protein Mlx in DNA binding and glucose-regulated transcription.Assembly of b/HLH/z proteins c-Myc, Max, and Mad1 with cognate DNA: importance of protein-protein and protein-DNA interactions.Contrasting Patterns in the Evolution of Vertebrate MLX Interacting Protein (MLXIP) and MLX Interacting Protein-Like (MLXIPL) Genes.Symmetrical Dose-Dependent DNA-Methylation Profiles in Children with Deletion or Duplication of 7q11.23Dietary Macronutrient Composition Directs ChREBP Isoform Expression and Glucose Metabolism in Mice.Glucose-mediated transactivation of carbohydrate response element-binding protein requires cooperative actions from Mondo conserved regions and essential trans-acting factor 14-3-3Identification of transcripts with enriched expression in the developing and adult pancreas.Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population.Metabolite regulation of nucleo-cytosolic trafficking of carbohydrate response element-binding protein (ChREBP): role of ketone bodies.ChREBP promotes the differentiation of leukemia-initiating cells to inhibit leukemogenesis through the TXNIP/RUNX1 pathways.ChREBP, a glucose-responsive transcriptional factor, enhances glucose metabolism to support biosynthesis in human cytomegalovirus-infected cells.Genetic basis of cognitive disability.Integration of ChREBP-Mediated Glucose Sensing into Whole Body Metabolism.The Role of Carbohydrate Response Element Binding Protein in Intestinal and Hepatic Fructose Metabolism.The regulation and role of carbohydrate response element binding protein in metabolic homeostasis and disease.Target metabolomics revealed complementary roles of hexose- and pentose-phosphates in the regulation of carbohydrate-dependent gene expression.Regulation of nuclear import/export of carbohydrate response element-binding protein (ChREBP): interaction of an alpha-helix of ChREBP with the 14-3-3 proteins and regulation by phosphorylation.
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WBSCR14, a gene mapping to the Williams--Beuren syndrome deleted region, is a new member of the Mlx transcription factor network
description
2001 nî lūn-bûn
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2001 թուականի Մարտին հրատարակուած գիտական յօդուած
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2001 թվականի մարտին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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WBSCR14, a gene mapping to the ...... x transcription factor network
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WBSCR14, a gene mapping to the ...... x transcription factor network
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WBSCR14, a gene mapping to the ...... x transcription factor network
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WBSCR14, a gene mapping to the ...... x transcription factor network
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WBSCR14, a gene mapping to the ...... x transcription factor network
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WBSCR14, a gene mapping to the ...... x transcription factor network
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WBSCR14, a gene mapping to the ...... x transcription factor network
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WBSCR14, a gene mapping to the ...... x transcription factor network
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WBSCR14, a gene mapping to the ...... x transcription factor network
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WBSCR14, a gene mapping to the ...... x transcription factor network
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WBSCR14, a gene mapping to the ...... x transcription factor network
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WBSCR14, a gene mapping to the ...... x transcription factor network
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WBSCR14, a gene mapping to the ...... x transcription factor network
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10.1093/HMG/10.6.617
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2001-03-15T00:00:00Z