Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations
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Genomic and genic deletions of the FOX gene cluster on 16q24.1 and inactivating mutations of FOXF1 cause alveolar capillary dysplasia and other malformationsImpaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice.Preparing for the first breath: genetic and cellular mechanisms in lung developmentOesophageal atresia, tracheo-oesophageal fistula, and the VACTERL association: review of genetics and epidemiologyGenetic susceptibility to Barrett's oesophagus: Lessons from early studiesThe genetic landscape and clinical implications of vertebral anomalies in VACTERL associationMultiple knockout mouse models reveal lincRNAs are required for life and brain developmentForkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage responseAbnormal notochord branching is associated with foregut malformations in the adriamycin treated mouse modelPulmonary mastocytosis and enhanced lung inflammation in mice heterozygous null for the Foxf1 geneHOXA13 Is essential for placental vascular patterning and labyrinth endothelial specificationFoxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septationFoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestineForkhead box F1 is essential for migration of mesenchymal cells and directly induces integrin-beta3 expressionSonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowthHedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordiaThe evolution of Fox genes and their role in development and diseaseThe tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse.Foxp1/2/4-NuRD interactions regulate gene expression and epithelial injury response in the lung via regulation of interleukin-6Pathogenetics of alveolar capillary dysplasia with misalignment of pulmonary veinsEpigenetic inactivation of the potential tumor suppressor gene FOXF1 in breast cancer.The OSR1 rs12329305 polymorphism contributes to the development of congenital malformations in cases of stillborn/neonatal deathDiversity, topographic differentiation, and positional memory in human fibroblasts.Sonic hedgehog controls growth of external genitalia by regulating cell cycle kinetics.Sonic hedgehog signaling in the lung. From development to disease.FOXF1 mediates mesenchymal stem cell fusion-induced reprogramming of lung cancer cellsAnalysis of FOXF1 and the FOX gene cluster in patients with VACTERL associationPolymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus.Resident tissue-specific mesenchymal progenitor cells contribute to fibrogenesis in human lung allograftsComparative analyses of lung transcriptomes in patients with alveolar capillary dysplasia with misalignment of pulmonary veins and in foxf1 heterozygous knockout miceAlveolar capillary dysplasiaGene expression signatures identify novel regulatory pathways during murine lung development: implications for lung tumorigenesis.Molecular and clinical analyses of 16q24.1 duplications involving FOXF1 identify an evolutionarily unstable large minisatelliteThe p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 functionStem cell in gastrointestinal structure and neoplastic development.Impaired mesenchymal cell function in Gata4 mutant mice leads to diaphragmatic hernias and primary lung defects.A Shh-Foxf-Fgf18-Shh Molecular Circuit Regulating Palate Development.Forkhead Box F1 promotes breast cancer cell migration by upregulating lysyl oxidase and suppressing Smad2/3 signalingGenetic and cellular mechanisms regulating anterior foregut and esophageal development.Targeted Resequencing of 29 Candidate Genes and Mouse Expression Studies Implicate ZIC3 and FOXF1 in Human VATER/VACTERL Association.
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P2860
Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations
description
2001 nî lūn-bûn
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2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Haploinsufficiency of the fork ...... lung and foregut malformations
@ast
Haploinsufficiency of the fork ...... lung and foregut malformations
@en
Haploinsufficiency of the fork ...... lung and foregut malformations
@en-gb
Haploinsufficiency of the fork ...... lung and foregut malformations
@nl
type
label
Haploinsufficiency of the fork ...... lung and foregut malformations
@ast
Haploinsufficiency of the fork ...... lung and foregut malformations
@en
Haploinsufficiency of the fork ...... lung and foregut malformations
@en-gb
Haploinsufficiency of the fork ...... lung and foregut malformations
@nl
prefLabel
Haploinsufficiency of the fork ...... lung and foregut malformations
@ast
Haploinsufficiency of the fork ...... lung and foregut malformations
@en
Haploinsufficiency of the fork ...... lung and foregut malformations
@en-gb
Haploinsufficiency of the fork ...... lung and foregut malformations
@nl
P2093
P921
P3181
P1433
P1476
Haploinsufficiency of the fork ...... lung and foregut malformations
@en
P2093
M Mahlapuu
P Carlsson
S Enerbäck
P304
P3181
P407
P577
2001-06-01T00:00:00Z