A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
about
A human aminoacyl-tRNA synthetase as a regulator of angiogenesisNonconventional involvement of LysRS in the molecular mechanism of USF2 transcriptional activity in FcepsilonRI-activated mast cellsCrystal structure of a human aminoacyl-tRNA synthetase cytokineThe matricellular protein cysteine-rich protein 61 (CCN1/Cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathyEvolution of function of a fused metazoan tRNA synthetaseA new gamma-interferon-inducible promoter and splice variants of an anti-angiogenic human tRNA synthetaseCrystal structure of human tryptophanyl-tRNA synthetase catalytic fragment: insights into substrate recognition, tRNA binding, and angiogenesis activityA short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetaseFunctional and Crystal Structure Analysis of Active Site Adaptations of a Potent Anti-Angiogenic Human tRNA SynthetaseCatalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic statesThe structure of tryptophanyl-tRNA synthetase from Giardia lamblia reveals divergence from eukaryotic homologsCrystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase.The aminoacyl-tRNA synthetases of Drosophila melanogasterThe mouse retina as an angiogenesis model.Aminoacyl-Transfer RNA Synthetase Deficiency Promotes Angiogenesis via the Unfolded Protein Response PathwayChemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction.WHEP domains direct noncanonical function of glutamyl-Prolyl tRNA synthetase in translational control of gene expressionFunctional expansion of human tRNA synthetases achieved by structural inventionstRNA synthetase: tRNA aminoacylation and beyondVEGF, not VEGFR2, is associated with the angiogenesis effect of mini-TyrRS/mini-TrpRS in human umbilical vein endothelial cells in hypoxiaEffect of mini-tyrosyl-tRNA synthetase on ischemic angiogenesis, leukocyte recruitment, and vascular permeabilityAminoacyl-tRNA synthetases: versatile players in the changing theater of translation.Biologically active fragment of a human tRNA synthetase inhibits fluid shear stress-activated responses of endothelial cells.Protein multifunctionality: principles and mechanisms.Structure of human tryptophanyl-tRNA synthetase in complex with tRNATrp reveals the molecular basis of tRNA recognition and specificity.Orthogonal use of a human tRNA synthetase active site to achieve multifunctionalityDissociating quaternary structure regulates cell-signaling functions of a secreted human tRNA synthetaseMisfolded human tRNA isodecoder binds and neutralizes a 3' UTR-embedded Alu elementTemporal genome expression profile analysis during t-cell-mediated colitis: identification of novel targets and pathways.Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis.Fibrosis and diseases of the eye.Proteomic analysis of human hepatoma cells expressing methionine adenosyltransferase I/III: Characterization of DDX3X as a target of S-adenosylmethionineA post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity.Overexpressed tryptophanyl-tRNA synthetase, an angiostatic protein, enhances oral cancer cell invasiveness.Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells.Small interfering RNA knockdown of mini-TyrRS and mini-TrpRS effects angiogenesis in human umbilical vein endothelial cells in hypoxic cultureAminoacyl-tRNA synthetase complexes: molecular multitasking revealed.Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stressGain-of-function mutational activation of human tRNA synthetase procytokineHypothesis: sarcoidosis is a STAT1-mediated disease.
P2860
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P2860
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis
@nl
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
@ast
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
@en
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
@en-gb
type
label
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis
@nl
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
@ast
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
@en
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
@en-gb
prefLabel
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis
@nl
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
@ast
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
@en
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
@en-gb
P2093
P2860
P3181
P356
P1476
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
@en
P2093
Atsushi Otani
Bonnie M Slike
David Cheresh
Karen Kinder
Karla L Ewalt
Martin Friedlander
Michael I Dorrell
Paul Schimmel
P2860
P304
P3181
P356
10.1073/PNAS.012601899
P407
P577
2002-01-02T00:00:00Z