Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle
about
Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffoldsA novel role for the nuclear membrane protein emerin in association of the centrosome to the outer nuclear membraneThe inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleusCoupling of the nucleus and cytoplasm: role of the LINC complexEmerin-prelamin A interplay in human fibroblastsStructural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffnessMammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processesNesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarizationLamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelopeMultiple roles for emerin: implications for Emery-Dreifuss muscular dystrophyThe nuclear envelope LEM-domain protein emerinThe Nesprin family member ANC-1 regulates synapse formation and axon termination by functioning in a pathway with RPM-1 and β-CateninCytoskeletal tension induces the polarized architecture of the nucleus.Structure of Sad1-UNC84 Homology (SUN) Domain Defines Features of Molecular Bridge in Nuclear EnvelopeNuclear envelope: positioning nuclei and organizing synapsesMammalian microtubule P-body dynamics are mediated by nesprin-1.Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cellsThe nuclear envelope at a glanceSUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in miceNesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeletonMuscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organizationLamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement.Opposing microtubule motors drive robust nuclear dynamics in developing muscle cells.Emerin organizes actin flow for nuclear movement and centrosome orientation in migrating fibroblasts.Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis.Emergence of a prestressed eukaryotic nucleus during cellular differentiation and developmentLinker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.Nesprin 1 is critical for nuclear positioning and anchorageLamin-binding ProteinsNesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscleStabilization of the spectrin-like domains of nesprin-1α by the evolutionarily conserved "adaptive" domain.Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope.Disruption of both nesprin 1 and desmin results in nuclear anchorage defects and fibrosis in skeletal muscle.Several novel nuclear envelope transmembrane proteins identified in skeletal muscle have cytoskeletal associations.UNC-83 IS a KASH protein required for nuclear migration and is recruited to the outer nuclear membrane by a physical interaction with the SUN protein UNC-84LINC complexes in health and disease.A novel locus for dilated cardiomyopathy maps to canine chromosome 8Untethering the nuclear envelope and cytoskeleton: biologically distinct dystonias arising from a common cellular dysfunctionSUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeletonLarge-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins
P2860
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P2860
Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@ast
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@en
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@en-gb
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@nl
type
label
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@ast
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@en
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@en-gb
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@nl
prefLabel
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@ast
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@en
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@en-gb
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@nl
P2093
P50
P3181
P356
P1476
Nesprin-2 is a multi-isomeric ...... lar network in skeletal muscle
@en
P2093
Cassandra D Ragnauth
Derek T Warren
Jeremy N Skepper
Juliet A Ellis
Nathalie F Worth
Peter L Weissberg
P304
P3181
P356
10.1242/JCS.01642
P407
P577
2005-01-25T00:00:00Z