GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis
about
Disease-associated mutations prevent GPR56-collagen III interactionExpression profile of the entire family of Adhesion G protein-coupled receptors in mouse and ratDisease-associated GPR56 mutations cause bilateral frontoparietal polymicrogyria via multiple mechanismsThe N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activityGPR56 Regulates VEGF production and angiogenesis during melanoma progressionThe orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancerNovel endogenous angiogenesis inhibitors and their therapeutic potentialTransglutaminase is a tumor cell and cancer stem cell survival factorGpr126 functions in Schwann cells to control differentiation and myelination via G-protein activationInternational Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptorsActivation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomainsCellular functions of tissue transglutaminasePhysiological, pathological, and structural implications of non-enzymatic protein-protein interactions of the multifunctional human transglutaminase 2Sticky signaling--adhesion class G protein-coupled receptors take the stageGPS autoproteolysis is required for CD97 to up-regulate the expression of N-cadherin that promotes homotypic cell-cell aggregationG protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and laminationComparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targetsGPR56 is essential for testis development and male fertility in miceGPR56 regulates pial basement membrane integrity and cortical laminationDependence of invadopodia function on collagen fiber spacing and cross-linking: computational modeling and experimental evidence.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsGPR56-regulated granule cell adhesion is essential for rostral cerebellar development.Identification of two GTP-independent alternatively spliced forms of tissue transglutaminase in human leukocytes, vascular smooth muscle, and endothelial cells.Adhesion GPCRs in Tumorigenesis.Experimental metastasis assay.Transglutaminase regulation of cell function.Orphan G protein-coupled receptors (GPCRs): biological functions and potential drug targetsDifferential patterns of allelic loss in estrogen receptor-positive infiltrating lobular and ductal breast cancer.GPR56 as a novel marker identifying the CD56dull CD16+ NK cell subset both in blood stream and in inflamed peripheral tissues.A novel GPR56 mutation causes bilateral frontoparietal polymicrogyriaSpecific expression of GPR56 by human cytotoxic lymphocytes.GPR56 in cancer progression: current status and future perspective.Effects on human transcriptome of mutated BRCA1 BRCT domain: a microarray study.GPR56 and the developing cerebral cortex: cells, matrix, and neuronal migrationThe adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development.The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα12/13 and RhoACUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.Disease-associated mutations affect GPR56 protein trafficking and cell surface expression.Activity-regulating structural changes and autoantibody epitopes in transglutaminase 2 assessed by hydrogen/deuterium exchange.
P2860
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P2860
GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis
description
2006 nî lūn-bûn
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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2006 թվականի հունիսին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@ast
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@en
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@en-gb
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@nl
type
label
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@ast
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@en
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@en-gb
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@nl
prefLabel
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@ast
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@en
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@en-gb
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@nl
P2093
P2860
P921
P3181
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P1476
GPR56, an atypical G protein-c ...... ma tumor growth and metastasis
@en
P2093
Jeremy D Hearn
Shahinoor Begum
P2860
P304
P3181
P356
10.1073/PNAS.0602681103
P407
P577
2006-06-13T00:00:00Z