Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation
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NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin RemodelingSpecific domains of nucleolin interact with Hdm2 and antagonize Hdm2-mediated p53 ubiquitinationCharacterisation of the interface between nucleophosmin (NPM) and p53: potential role in p53 stabilisationMyeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3GNL3L depletion destabilizes MDM2 and induces p53-dependent G2/M arrestAKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosisMYBBP1A suppresses breast cancer tumorigenesis by enhancing the p53 dependent anoikisNucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosomep130Cas mediates the transforming properties of the anaplastic lymphoma kinase14-3-3 Binding to Pim-phosphorylated Ser166 and Ser186 of human Mdm2--Potential interplay with the PKB/Akt pathway and p14(ARF)Polo-like kinase-1 phosphorylates MDM2 at Ser260 and stimulates MDM2-mediated p53 turnoverA newly identified Pirh2 substrate SCYL1-BP1 can bind to MDM2 and accelerate MDM2 self-ubiquitinationAberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2Nucleophosmin: from structure and function to disease developmentMolecules that target nucleophosmin for cancer treatment: an updateGuarding the 'translation apparatus': defective ribosome biogenesis and the p53 signaling pathwayStructure and Function of the N-terminal Nucleolin Binding Domain of Nuclear Valosin-containing Protein-like 2 (NVL2) Harboring a Nucleolar Localization SignalStructural polymorphism in the N-terminal oligomerization domain of NPM1Insights into the regulation of neuronal viability by nucleophosmin/B234-thiouridine inhibits rRNA synthesis and causes a nucleolar stress responseA phthalimide derivative that inhibits centrosomal clustering is effective on multiple myelomaNucleolar release of Hand1 acts as a molecular switch to determine cell fateCharacterization of centrosomal association of nucleophosmin/B23 linked to Crm1 activityPolyamine depletion induces nucleophosmin modulating stability and transcriptional activity of p53 in intestinal epithelial cellsProtein NPM3 interacts with the multifunctional nucleolar protein B23/nucleophosmin and inhibits ribosome biogenesisNucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gammaRole of nucleophosmin in embryonic development and tumorigenesisNucleophosmin is required for DNA integrity and p19Arf protein stabilityRegulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11.GLTSCR2 is an upstream negative regulator of nucleophosmin in cervical cancer.Nucleolar protein GLTSCR2 stabilizes p53 in response to ribosomal stressesTherapeutic considerations for Mdm2: not just a one trick ponyCellular stress stimulates nuclear localization signal (NLS) independent nuclear transport of MRJ.Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins.A proteomics approach for the identification of nucleophosmin and heterogeneous nuclear ribonucleoprotein C1/C2 as chromatin-binding proteins in response to DNA double-strand breaks.Proteome analysis of proliferative response of bystander cells adjacent to cells exposed to ionizing radiationA novel site of AKT-mediated phosphorylation in the human MDM2 onco-protein.Viral oncogene-induced DNA damage response is activated in Kaposi sarcoma tumorigenesis.Nucleophosmin phosphorylation by v-cyclin-CDK6 controls KSHV latency.NPM phosphorylation stimulates Cdk1, overrides G2/M checkpoint and increases leukemic blasts in mice
P2860
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P2860
Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@ast
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@en
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@en-gb
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@nl
type
label
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@ast
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@en
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@en-gb
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@nl
prefLabel
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@ast
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@en
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@en-gb
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@nl
P2093
P50
P3181
P1433
P1476
Nucleolar protein NPM interact ...... from HDM2-mediated degradation
@en
P2093
David Meek
Marikki Laiho
Sari Kurki
Taija M Kiviharju
P304
P3181
P356
10.1016/S1535-6108(04)00110-2
P407
P577
2004-05-01T00:00:00Z