LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress - sprookjes - yvandenbroek - TriplyDB

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

http://www.wikidata.org/entity/Q24294466

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Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector Biomedical and clinical promises of human pluripotent stem cells for neurological disorders Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation The role of oxidative stress in Parkinson's disease Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies Induced neuronal cells: how to make and define a neuron Amniotic Fluid Stem Cells: A Novel Source for Modeling of Human Genetic Diseases The Application of Human iPSCs in Neurological Diseases: From Bench to Bedside The Progress of Induced Pluripotent Stem Cells as Models of Parkinson's Disease Recent Advances in Disease Modeling and Drug Discovery for Diabetes Mellitus Using Induced Pluripotent Stem Cells Functional Evaluations of Genes Disrupted in Patients with Tourette's Disorder.Induced pluripotent stem cells for modeling neurological disorders Epigenetic Research of Neurodegenerative Disorders Using Patient iPSC-Based Models Induced pluripotent stem cells in Parkinson's disease: scientific and clinical challenges Induced Pluripotency and Gene Editing in Disease Modelling: Perspectives and Challenges Αlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's Disease Understanding the molecular basis of autism in a dish using hiPSCs-derived neurons from ASD patients Deconvoluting the complexity of autophagy and Parkinson's disease for potential therapeutic purpose Cardiovascular Disease Modeling Using Patient-Specific Induced Pluripotent Stem Cells Applications of Induced Pluripotent Stem Cells in Studying the Neurodegenerative Diseases Using iPS Cells toward the Understanding of Parkinson's Disease Alzheimer's in 3D culture: challenges and perspectives Induced pluripotent stem cell technology and direct conversion: new possibilities to study and treat Parkinson's disease Patient-specific induced pluripotent stem cells in neurological disease modeling: the importance of nonhuman primate models Cellular models to investigate biochemical pathways in Parkinson's disease iPSCs and small molecules: a reciprocal effort towards better approaches for drug discovery Longitudinal measures of proteostasis in live neurons: features that determine fate in models of neurodegenerative disease Induced pluripotent stem cells as a disease modeling and drug screening platform The genomic stability of induced pluripotent stem cells Proceedings: consideration of genetics in the design of induced pluripotent stem cell-based models of complex disease Programming and Reprogramming Cellular Age in the Era of Induced Pluripotency Modeling neurological disorders by human induced pluripotent stem cells Neurodegenerative diseases in a dish: the promise of iPSC technology in disease modeling and therapeutic discovery Stem cells in the nervous system Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson's disease Physiological characterisation of human iPS-derived dopaminergic neurons Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds

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LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

http://www.wikidata.org/entity/Q24294466

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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prefLabel

LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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J.STEM.2011.01.013

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LRRK2 mutant iPSC-derived DA n ...... eptibility to oxidative stress

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Aleksandr Shcheglovitov

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Birgitt Schüle

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Blake Byers

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Branden Cord

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Ha Nam Nguyen

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James Byrne

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Prachi Gujar

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Renee Reijo Pera

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Ricardo E Dolmetsch

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Theo D Palmer

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P2860

The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age

alpha-Synuclein and neuronal cell death

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

Kinase activity of mutant LRRK2 mediates neuronal toxicity

The familial Parkinsonism gene LRRK2 regulates neurite process morphology

Disease-specific induced pluripotent stem cells

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

Enhanced generation of induced pluripotent stem cells from a subpopulation of human fibroblasts

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

alpha-Synuclein locus triplication causes Parkinson's disease

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267-280

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scholarly article

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995191

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10.1016/J.STEM.2011.01.013

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3

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8

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2011-03-01T00:00:00Z

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50249565

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21362567

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cellular response to oxidative stress

Leucine rich repeat kinase 2

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3578553

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