DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation
about
Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosomeALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertilityThe histone demethylase LSD1/KDM1A promotes the DNA damage responseHuman ALKBH7 is required for alkylation and oxidation-induced programmed necrosisDuplex interrogation by a direct DNA repair protein in search of base damageSwitching demethylation activities between AlkB family RNA/DNA demethylases through exchange of active-site residuesTranscriptome-wide mapping reveals reversible and dynamic N(1)-methyladenosine methylomeNoncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase.The atomic resolution structure of human AlkB homolog 7 (ALKBH7), a key protein for programmed necrosis and fat metabolismAdaptive Response Enzyme AlkB Preferentially Repairs 1-Methylguanine and 3-Methylthymine Adducts in Double-Stranded DNAOncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological ConditionsThe oxidative demethylase ALKBH3 marks hyperactive gene promoters in human cancer cellsA comprehensive view of the epigenetic landscape part I: DNA methylation, passive and active DNA demethylation pathways and histone variants.Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities.Correlations between ASCC3 Gene Polymorphisms and Chronic Hepatitis B in a Chinese Han Population.The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond.DNA repair is indispensable for survival after acute inflammation.The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage.DNA methylation levels and long-term trihalomethane exposure in drinking water: an epigenome-wide association study.Alkbh2 protects against lethality and mutation in primary mouse embryonic fibroblasts.A short hairpin RNA screen of interferon-stimulated genes identifies a novel negative regulator of the cellular antiviral response.Rhein Inhibits AlkB Repair Enzymes and Sensitizes Cells to Methylated DNA DamageThe Cardiomyocyte RNA-Binding Proteome: Links to Intermediary Metabolism and Heart Disease.Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine LesionsFluorescence Monitoring of the Oxidative Repair of DNA Alkylation Damage by ALKBH3, a Prostate Cancer Marker.The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants.Probing DNA by 2-OG-dependent dioxygenase.AlkB homolog 3-mediated tRNA demethylation promotes protein synthesis in cancer cells.Nucleic acid oxidation in DNA damage repair and epigeneticsDNA repair by reversal of DNA damage.The roles of Jumonji-type oxygenases in human disease.Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans.Non-homologous functions of the AlkB homologs.Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans.CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer.UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same GeneOncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents.Functions and regulation of the Brr2 RNA helicase during splicing.Regulation of DNA Alkylation Damage Repair: Lessons and Therapeutic Opportunities.The Epitranscriptome of Noncoding RNAs in Cancer.
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DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@ast
DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@en
DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@en-gb
DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@nl
type
label
DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@ast
DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@en
DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@en-gb
DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@nl
prefLabel
DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@ast
DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@en
DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@en-gb
DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@nl
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DNA unwinding by ASCC3 helicas ...... and cancer cell proliferation
@en
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Feizhen Wu
J Wade Harper
Keyjung Park
Li-Jun Xiong
Mathew E Sowa
Nima Mosammaparast
Sebastian Dango
Steve Gygi
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P304
P3181
P356
10.1016/J.MOLCEL.2011.08.039
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P50
P577
2011-11-04T00:00:00Z