DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1
about
Disturbed clockwork resetting in Sharp-1 and Sharp-2 single and double mutant micePolymorphism in the PER3 promoter associates with diurnal preference and delayed sleep phase disorder.DEC1 binding to the proximal promoter of CYP3A4 ascribes to the downregulation of CYP3A4 expression by IL-6 in primary human hepatocytesPhotochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor.The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter.SUMOylation of DEC1 protein regulates its transcriptional activity and enhances its stability.Pregnane X receptor is required for interleukin-6-mediated down-regulation of cytochrome P450 3A4 in human hepatocytes.Stra13/DEC1 and DEC2 inhibit sterol regulatory element binding protein-1c in a hypoxia-inducible factor-dependent mechanismCLOCKWORK ORANGE Enhances PERIOD Mediated Rhythms in Transcriptional Repression by Antagonizing E-box Binding by CLOCK-CYCLEThe rexinoid bexarotene represses cyclin D1 transcription by inducing the DEC2 transcriptional repressor.Regulation of the Mechanism of TWIST1 Transcription by BHLHE40 and BHLHE41 in Cancer Cells.Molecular circadian rhythms in central and peripheral clocks in mammals.Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease.A fluorescence spotlight on the clockwork development and metabolism of bone.Molecular modulators of the circadian clock: lessons from flies and mice.Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrug.Differentiated embryo chondrocyte 1 (DEC1) represses PPARγ2 gene through interacting with CCAAT/enhancer binding protein β (C/EBPβ).Effects of mutants in bHLH region on structure stability and protein-DNA binding energy in DECs.Circadian rhythmicity: A functional connection between differentiated embryonic chondrocyte-1 (DEC1) and small heterodimer partner (SHP).Downregulation of DEC1 contributes to the neurotoxicity induced by MPP+ by suppressing PI3K/Akt/GSK3β pathway.Genetic interaction of Per1 and Dec1/2 in the regulation of circadian locomotor activity.
P2860
0929775002c8a9de8b3632fd28fa403b1aae85ba093226c67ebc8e8e1f31299a1fcc0418611b34195c761fb61dcfc80d0ae8becfb153652ed6e8495f60b57373c31d127e84fb16390186176cad00eb89684c6c6fad573565aac5b99fc7fe9943079b321ca72dd48e44bd441c37fde41b95a69e9daa31f6d3bedae84d26af7d696074abfb7256b4b3ffacdddec2e924679f342b52333cb6ec622b40941753fcaacbd36ab33f27436767d9f7e53f8f2c8250cb6273db04b75c86b12cb4351aaf48c150f625df8e2fc0
P248
Q27300842-38BB77DB-1183-4F10-BE8C-9667DA2A88EBQ33578139-079DBAD0-2A29-44FC-9B71-EF17E28934E3Q33869682-6B1A4A92-BAE1-436A-BA12-E3FC0DC72D81Q33967328-952F45FF-6B5F-4939-9F0D-FB8BEC1DD8F2Q33968314-250213F2-F75A-480E-87DA-62A7CAD56164Q33988687-AD828600-8928-4A48-8466-ACF7C7C56146Q34101899-D70BF199-6B7E-4EE3-AA39-1C47D282ADA7Q34598057-13C343DD-EE5D-451B-A876-3E0FBA7B58BDQ36182829-2F49AA15-D587-4803-830A-E1F165C82494Q36241281-0C8E72F4-4A45-4993-B954-86652DFB79EEQ36289517-F143B37B-E93C-4EAB-9166-C3C6CEBE9303Q36799431-57B5A92B-C911-4A09-A45A-FB918F5F987DQ37739209-BFE58A08-95FD-4F5F-A64F-D6672948E051Q37902096-648BB294-80DB-452F-8B84-DEDE3033CC91Q38968773-61A65223-882B-4478-8002-AA5821359111Q39200965-3066E451-ED85-445E-877E-C8B886762552Q41864403-15EB708A-A4FB-4E12-BC9B-83C550ECDEECQ46505131-B99AB00B-1352-4F6D-B848-03A61EFCBA31Q47967476-AAE7A01E-549B-48CC-B59C-482453C35236Q48362528-CC11DC5D-52B0-42D4-8C88-8EAC2781EA74Q48730406-79687997-1CF3-4CFE-AE40-64AD4DB3BC5F
P2860
DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
DNA binding, but not interacti ...... on of the circadian gene mPer1
@ast
DNA binding, but not interacti ...... on of the circadian gene mPer1
@en
DNA binding, but not interacti ...... on of the circadian gene mPer1
@en-gb
DNA binding, but not interacti ...... on of the circadian gene mPer1
@nl
type
label
DNA binding, but not interacti ...... on of the circadian gene mPer1
@ast
DNA binding, but not interacti ...... on of the circadian gene mPer1
@en
DNA binding, but not interacti ...... on of the circadian gene mPer1
@en-gb
DNA binding, but not interacti ...... on of the circadian gene mPer1
@nl
prefLabel
DNA binding, but not interacti ...... on of the circadian gene mPer1
@ast
DNA binding, but not interacti ...... on of the circadian gene mPer1
@en
DNA binding, but not interacti ...... on of the circadian gene mPer1
@en-gb
DNA binding, but not interacti ...... on of the circadian gene mPer1
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
DNA binding, but not interacti ...... on of the circadian gene mPer1
@en
P2093
Bingfang Yan
Dongfang Yang
Jirong Liu
Xiulong Song
Yuzhong Ma
P2860
P304
P3181
P356
10.1042/BJ20040592
P407
P577
2004-09-15T00:00:00Z