Substrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2)
about
Alkaline ceramidase 2 (ACER2) and its product dihydrosphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cellsAlkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the BrainCREST--a large and diverse superfamily of putative transmembrane hydrolases.Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.Discovery and evaluation of inhibitors of human ceramidase.p38 mitogen-activated protein kinase/activator protein-1 involved in serum deprivation-induced human alkaline ceramidase 2 upregulationAcid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expressionActivity of neutral and alkaline ceramidases on fluorogenic N-acylated coumarin-containing aminodiols.Metabolic Conversion of Ceramides in HeLa Cells - A Cholesteryl Phosphocholine Delivery Approach.Triangulated mal-signaling in Alzheimer's disease: roles of neurotoxic ceramides, ER stress, and insulin resistance reviewedAlkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage responseDeficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy.Identification and biochemical characterization of Laodelphax striatellus neutral ceramidaseCeramide signaling in mammalian epidermis.Alkaline ceramidase 2 is a novel direct target of p53 and induces autophagy and apoptosis through ROS generation.Nuclear sphingolipid metabolism.Sphingolipid metabolism and neutral sphingomyelinases.Sphingolipids and mitochondrial apoptosis.Molecular biomarkers of phospholipidosis in rat blood and heart after amiodarone treatment.Ceramidases, roles in sphingolipid metabolism and in health and disease.Purification and biochemical characterization of membrane-bound neutral ceramidase from camel brain (Camelus dromedarius).Implication of sphingosine-1-phosphate signaling in diseases: molecular mechanism and therapeutic strategies.Role of sphingosine kinase localization in sphingolipid signalingA neutral ceramidase, NlnCDase, is involved in the stress responses of brown planthopper, Nilaparvata lugens (Stål).Tumor suppressor p53 links ceramide metabolism to DNA damage response through alkaline ceramidase 2.Membrane topology of yeast alkaline ceramidase YPC1.
P2860
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P2860
Substrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2)
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@ast
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@en
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@en-gb
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@nl
type
label
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@ast
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@en
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@en-gb
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@nl
prefLabel
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@ast
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@en
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@en-gb
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@nl
P2093
P2860
P921
P356
P1476
Substrate specificity, membran ...... alkaline ceramidase 2 (ACER2)
@en
P2093
Cungui Mao
Jacek Bielawski
Ruijuan Xu
Zdzislaw M Szulc
P2860
P304
P356
10.1074/JBC.M109.069203
P407
P577
2010-01-20T00:00:00Z