Parkin ubiquitinates and promotes the degradation of RanBP2
about
RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolismParkin mono-ubiquitinates Bcl-2 and regulates autophagyParkin Regulation and Neurodegenerative DisordersRBR E3 ubiquitin ligases: new structures, new insights, new questionsMechanisms, regulation and consequences of protein SUMOylationAberrant Expression of Histone Deacetylases 4 in Cognitive Disorders: Molecular Mechanisms and a Potential TargetParkin occurs in a stable, non-covalent, approximately 110-kDa complex in brainThe PINK1/Parkin pathway regulates mitochondrial morphologyLoss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromesIdentification and characterization of a novel endogenous murine parkin mutation.PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice.Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction.Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.Biology and biophysics of the nuclear pore complex and its componentsParkin mediates the degradation-independent ubiquitination of Hsp70A short N-terminal domain of HDAC4 preserves photoreceptors and restores visual function in retinitis pigmentosa.Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).Ubiquitin proteolytic system: focus on SUMO.The ring between ring fingers (RBR) protein familyClass IIA HDACs in the regulation of neurodegeneration.Emerging extranuclear roles of protein SUMOylation in neuronal function and dysfunctionProgress in the pathogenesis and genetics of Parkinson's disease.Histone deacetylases: salesmen and customers in the post-translational modification market.Protein SUMOylation in neuropathological conditions.The role of parkin in familial and sporadic Parkinson's disease.Targets and consequences of protein SUMOylation in neurons.Protein modifications involved in neurotransmitter and gasotransmitter signaling.Parkin, A Top Level Manager in the Cell's Sanitation Department.Cross-functional E3 ligases Parkin and C-terminus Hsp70-interacting protein in neurodegenerative disorders.Mammalian target of rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimer's disease?Regulation of Parkin E3 ubiquitin ligase activity.Molecular targets underlying SUMO-mediated neuroprotection in brain ischemia.SUMO and Parkinson's disease.The oncogene eIF4E reprograms the nuclear pore complex to promote mRNA export and oncogenic transformation.Twenty years since the discovery of the parkin gene.Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin.Sumoylation: Implications for Neurodegenerative Diseases.Neddylation positively regulates the ubiquitin E3 ligase activity of parkin.Ubiquitin proteasome system networks in the neurological disorders
P2860
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P2860
Parkin ubiquitinates and promotes the degradation of RanBP2
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Parkin ubiquitinates and promotes the degradation of RanBP2
@ast
Parkin ubiquitinates and promotes the degradation of RanBP2
@en
Parkin ubiquitinates and promotes the degradation of RanBP2
@en-gb
Parkin ubiquitinates and promotes the degradation of RanBP2
@nl
type
label
Parkin ubiquitinates and promotes the degradation of RanBP2
@ast
Parkin ubiquitinates and promotes the degradation of RanBP2
@en
Parkin ubiquitinates and promotes the degradation of RanBP2
@en-gb
Parkin ubiquitinates and promotes the degradation of RanBP2
@nl
prefLabel
Parkin ubiquitinates and promotes the degradation of RanBP2
@ast
Parkin ubiquitinates and promotes the degradation of RanBP2
@en
Parkin ubiquitinates and promotes the degradation of RanBP2
@en-gb
Parkin ubiquitinates and promotes the degradation of RanBP2
@nl
P2093
P2860
P3181
P356
P1476
Parkin ubiquitinates and promotes the degradation of RanBP2
@en
P2093
Do Sik Min
Hyewhon Rhim
Kwang Chul Chung
Seung R Paik
P2860
P304
P3181
P356
10.1074/JBC.M504994200
P407
P50
P577
2005-12-06T00:00:00Z