An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A
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The role of RhoA and cytoskeleton in myofibroblast transformation in hyperoxic lung fibrosisNuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLSCapturing cooperative interactions with the PSI-MI formatMyocardin-Related Transcription Factor A Activation by Competition with WH2 Domain Proteins for Actin Binding.Induction of megakaryocyte differentiation drives nuclear accumulation and transcriptional function of MKL1 via actin polymerization and RhoA activationLamin A/C and emerin regulate MKL1-SRF activity by modulating actin dynamicsHuman PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm.Loss of γ-cytoplasmic actin triggers myofibroblast transition of human epithelial cells.RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling.ROCK and Rho: Promising therapeutic targets to ameliorate pulmonary fibrosis.Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts.Stereospecific Inhibitory Effects of CCG-1423 on the Cellular Events Mediated by Myocardin-Related Transcription Factor A.Actin binding to WH2 domains regulates nuclear import of the multifunctional actin regulator JMY.Interferon-induced mechanosensing defects impede apoptotic cell clearance in lupus.The cellular mastermind(?)-mechanotransduction and the nucleus.Smooth muscle hyperplasia due to loss of smooth muscle α-actin is driven by activation of focal adhesion kinase, altered p53 localization and increased levels of platelet-derived growth factor receptor-β.Novel insights into the disease etiology of laminopathies.The function of importin β1 is conserved in eukaryotes but the substrates may vary in organisms.Stretch-dependent smooth muscle differentiation in the portal vein-role of actin polymerization, calcium signaling, and microRNAs.Rho, nuclear actin, and actin-binding proteins in the regulation of transcription and gene expression.Role of nuclear Lamin A/C in cardiomyocyte functions.Cellular Levels of Signaling Factors Are Sensed by β-actin Alleles to Modulate Transcriptional Pulse Intensity.Nuclear roles for actin.The nucleus is a conserved mechanosensation and mechanoresponse organelle.Substrate stiffness-dependent regulation of the SRF-Mkl1 co-activator complex requires the inner nuclear membrane protein Emerin.Unravelling a new mechanism linking actin polymerization and gene transcription.A novel inhibitory mechanism of MRTF-A/B on the ICAM-1 gene expression in vascular endothelial cells.Phosphorylation acts positively and negatively to regulate MRTF-A subcellular localisation and activity.Cofilin nuclear-cytoplasmic shuttling affects cofilin-actin rod formation during stress.MRTFs- master regulators of EMT.Formin' actin in the nucleus.Transient α-helices in the disordered RPEL motifs of the serum response factor coactivator MKL1.Differences in the nuclear export mechanism between myocardin and myocardin-related transcription factor A.In search of novel targets for heart disease: myocardin and myocardin-related transcriptional cofactors.From Cytoskeleton to Gene Expression: Actin in the Nucleus.Regulation of genome organization and gene expression by nuclear mechanotransduction.Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas.
P2860
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P2860
An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
An actin-regulated importin α/ ...... rects nuclear import of MRTF-A
@ast
An actin-regulated importin α/ ...... rects nuclear import of MRTF-A
@en
An actin-regulated importin α/ ...... rects nuclear import of MRTF-A
@nl
type
label
An actin-regulated importin α/ ...... rects nuclear import of MRTF-A
@ast
An actin-regulated importin α/ ...... rects nuclear import of MRTF-A
@en
An actin-regulated importin α/ ...... rects nuclear import of MRTF-A
@nl
prefLabel
An actin-regulated importin α/ ...... rects nuclear import of MRTF-A
@ast
An actin-regulated importin α/ ...... rects nuclear import of MRTF-A
@en
An actin-regulated importin α/ ...... rects nuclear import of MRTF-A
@nl
P2860
P356
P1433
P1476
An actin-regulated importin α/ ...... rects nuclear import of MRTF-A
@en
P2093
Maria K Vartiainen
Rafał Pawłowski
P2860
P304
P356
10.1038/EMBOJ.2010.216
P407
P577
2010-09-03T00:00:00Z