Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase
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HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition.Deficiency of the zinc finger protein ZPR1 causes defects in transcription and cell cycle progressionFLASH is essential during early embryogenesis and cooperates with p73 to regulate histone gene transcriptionThe histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motifCDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-PModelling Robust Feedback Control Mechanisms That Ensure Reliable Coordination of Histone Gene Expression with DNA ReplicationThe histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cyclesThe architectural organization of human stem cell cycle regulatory machineryLearning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual information.Genome-wide analysis of regions similar to promoters of histone genesFidelity of histone gene regulation is obligatory for genome replication and stability.The dynamic organization of gene-regulatory machinery in nuclear microenvironmentsAssembly of the SLIP1-SLBP complex on histone mRNA requires heterodimerization and sequential binding of SLBP followed by SLIP1.Reprogramming the pluripotent cell cycle: restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells.A conserved interaction that is essential for the biogenesis of histone locus bodies.The subnuclear organization of histone gene regulatory proteins and 3' end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types.Pygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells.Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition.p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency.Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle.The abbreviated pluripotent cell cycle.Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cellsFunctional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development.Multilayered chromatin analysis reveals E2f, Smad and Zfx as transcriptional regulators of histones.Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion.Coordinate control and selective expression of the full complement of replication-dependent histone H4 genes in normal and cancer cells.The histone gene transcription factor HiNF-P stabilizes its cell cycle regulatory co-activator p220NPAT.Coordinating cell cycle-regulated histone gene expression through assembly and function of the Histone Locus Body.Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos.
P2860
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P2860
Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@ast
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@en
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@en-gb
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@nl
type
label
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@ast
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@en
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@en-gb
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@nl
prefLabel
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@ast
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@en
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@en-gb
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@nl
P2093
P2860
P921
P3181
P1476
Identification of HiNF-P, a ke ...... genes at the onset of S phase
@en
P2093
André J van Wijnen
Gary S Stein
Hayk Hovhannisyan
J Wade Harper
Janet L Stein
Partha Mitra
Ricardo Medina
Rong-Lin Xie
S Kaleem Zaidi
P2860
P304
P3181
P356
10.1128/MCB.23.22.8110-8123.2003
P407
P577
2003-11-01T00:00:00Z