PH domain of ELMO functions in trans to regulate Rac activation via Dock180
about
An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signalingStructure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5GEF what? Dock180 and related proteins help Rac to polarize cells in new waysIdentification of tyrosine residues on ELMO1 that are phosphorylated by the Src-family kinase Hck.Function of the N-terminus of zizimin1: autoinhibition and membrane targeting.The CDM superfamily protein MBC directs myoblast fusion through a mechanism that requires phosphatidylinositol 3,4,5-triphosphate binding but is independent of direct interaction with DCrkRegulation of small GTPases by GEFs, GAPs, and GDIsThe DOCK protein sponge binds to ELMO and functions in Drosophila embryonic CNS developmentStructural analysis of the carboxy terminal PH domain of pleckstrin bound to D-myo-inositol 1,2,3,5,6-pentakisphosphateStructural Basis of Membrane Targeting by the Dock180 Family of Rho Family Guanine Exchange Factors (Rho-GEFs)Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited formsSolution structure of the SH3 domain of DOCK180Bud3 activates Cdc42 to establish a proper growth site in budding yeast.Regulation of phagocytosis by Rho GTPasesELMO domains, evolutionary and functional characterization of a novel GTPase-activating protein (GAP) domain for Arf protein family GTPasesThe SH3 regulatory domain of the hematopoietic cell kinase Hck binds ELMO via its polyproline motif.Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.Regulation of focal adhesion and cell migration by ANKRD28-DOCK180 interactionApoptotic cell recognition receptors and scavenger receptors.Clearing the dead: apoptotic cell sensing, recognition, engulfment, and digestionA link between the cytoplasmic engulfment protein Elmo1 and the Mediator complex subunit Med31.Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivoThe RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons.A pathway for phagosome maturation during engulfment of apoptotic cellsIdentification of two signaling submodules within the CrkII/ELMO/Dock180 pathway regulating engulfment of apoptotic cells.Dictyostelium Dock180-related RacGEFs regulate the actin cytoskeleton during cell motility.Essential role of Elmo1 in Dock2-dependent lymphocyte migrationThe Sec14 homology domain regulates the cellular distribution and transforming activity of the Rho-specific guanine nucleotide exchange factor Dbs.A minimal Rac activation domain in the unconventional guanine nucleotide exchange factor Dock180.ClipR-59 interacts with Elmo2 and modulates myoblast fusion.The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity.A SPIKE1 signaling complex controls actin-dependent cell morphogenesis through the heteromeric WAVE and ARP2/3 complexesClearance of apoptotic cells by phagocytes.Activation of Rac1 by the guanine nucleotide exchange factor Dck1 is required for invasive filamentous growth in the pathogen Candida albicans.ELMO1 Directly Interacts with Gβγ Subunit to Transduce GPCR Signaling to Rac1 Activation in Chemotaxis.Drosophila ELMO/CED-12 interacts with Myoblast city to direct myoblast fusion and ommatidial organizationThe role of small GTPases in neuronal morphogenesis and polarity.I'm coming to GEF you: Regulation of RhoGEFs during cell migration.Arf GAPs: A family of proteins with disparate functions that converge on a common structure, the integrin adhesion complex.Shigella IpgB1 promotes bacterial entry through the ELMO-Dock180 machinery.
P2860
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P2860
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
@ast
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
@en
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
@nl
type
label
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
@ast
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
@en
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
@nl
prefLabel
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
@ast
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
@en
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
@nl
P2093
P2860
P50
P3181
P356
P1476
PH domain of ELMO functions in trans to regulate Rac activation via Dock180
@en
P2093
Colin deBakker
Cynthia Grimsley
Doris Klingele
Enrico Brugnera
Kent L Rossman
Lisa B Haney
Mingjian Lu
P2860
P2888
P304
P3181
P356
10.1038/NSMB800
P407
P577
2004-08-01T00:00:00Z
P5875
P6179
1002917807