A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement
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Recent advances in amyotrophic lateral sclerosisToward precision medicine in amyotrophic lateral sclerosisImpaired Autophagy and Defective Mitochondrial Function: Converging Paths on the Road to Motor Neuron DegenerationClinical and genetic basis of familial amyotrophic lateral sclerosisSOD1 misplacing and mitochondrial dysfunction in amyotrophic lateral sclerosis pathogenesisGenes and Pathways Involved in Adult Onset Disorders Featuring Muscle Mitochondrial DNA InstabilityOxidative stress and mitochondrial damage: importance in non-SOD1 ALSMutations in MDH2, Encoding a Krebs Cycle Enzyme, Cause Early-Onset Severe EncephalopathyGene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrityLoss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome cCharting Frontotemporal Dementia: From Genes to Networks.Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivoProtein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia ContinuumPathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates.Late onset spinal motor neuronopathy is caused by mutation in CHCHD10.CHCH10 mutations in an Italian cohort of familial and sporadic amyotrophic lateral sclerosis patients.Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.Spectrum of combined respiratory chain defects.Genotype-phenotype relationship in hereditary amyotrophic lateral sclerosis.Distinct Muscle Biopsy Findings in Genetically Defined Adult-Onset Motor Neuron DisordersA multi-center screening trial of rasagiline in patients with amyotrophic lateral sclerosis: Possible mitochondrial biomarker target engagement.Bovine and murine models highlight novel roles for SLC25A46 in mitochondrial dynamics and metabolism, with implications for human and animal health.Mitochondrial targeting sequence variants of the CHCHD2 gene are a risk for Lewy body disordersPreferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration in vivo.CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis.Mutation in the novel nuclear-encoded mitochondrial protein CHCHD10 in a family with autosomal dominant mitochondrial myopathy.An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic miceRare Variants in Neurodegeneration Associated Genes Revealed by Targeted Panel Sequencing in a German ALS Cohort.Mutational analysis of PRNP in Alzheimer's disease and frontotemporal dementia in China.Motor neuron disease in 2014. Biomarkers for ALS--in search of the Promised LandGenetic causes of amyotrophic lateral sclerosis: new genetic analysis methodologies entailing new opportunities and challenges.Disturbed mitochondrial dynamics and neurodegenerative disorders.Mitochondrial dynamism and the pathogenesis of Amyotrophic Lateral Sclerosis.Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis.Targeting mitochondrial metal dyshomeostasis for the treatment of neurodegeneration.New ALS-Related Genes Expand the Spectrum Paradigm of Amyotrophic Lateral Sclerosis.Optimization of a 3D Dynamic Culturing System for In Vitro Modeling of Frontotemporal Neurodegeneration-Relevant Pathologic Features.Parkin suppresses Drp1-independent mitochondrial divisionGenetics of FTLD: overview and what else we can expect from genetic studies.
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P2860
A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A mitochondrial origin for fro ...... is through CHCHD10 involvement
@ast
A mitochondrial origin for fro ...... is through CHCHD10 involvement
@en
A mitochondrial origin for fro ...... is through CHCHD10 involvement
@en-gb
A mitochondrial origin for fro ...... is through CHCHD10 involvement
@nl
type
label
A mitochondrial origin for fro ...... is through CHCHD10 involvement
@ast
A mitochondrial origin for fro ...... is through CHCHD10 involvement
@en
A mitochondrial origin for fro ...... is through CHCHD10 involvement
@en-gb
A mitochondrial origin for fro ...... is through CHCHD10 involvement
@nl
prefLabel
A mitochondrial origin for fro ...... is through CHCHD10 involvement
@ast
A mitochondrial origin for fro ...... is through CHCHD10 involvement
@en
A mitochondrial origin for fro ...... is through CHCHD10 involvement
@en-gb
A mitochondrial origin for fro ...... is through CHCHD10 involvement
@nl
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P50
P921
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A mitochondrial origin for fro ...... is through CHCHD10 involvement
@en
P2093
Annabelle Chaussenot
Anne de Septenville
Annie Verschueren
Charlotte Cochaud
Cécile Rouzier
Gaëlle Augé
Hiromi Sesaki
Isabelle Le Ber
Jean Pouget
Karine N'Guyen
P2860
P304
P3181
P356
10.1093/BRAIN/AWU138
P407
P577
2014-08-01T00:00:00Z