Human SIRT6 promotes DNA end resection through CtIP deacetylation
about
Sirtuins: molecular traffic lights in the crossroad of oxidative stress, chromatin remodeling, and transcriptionThe histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolismDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsSIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cellsRole of Deubiquitinating Enzymes in DNA RepairTargeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implicationsMetabolic modulation of chromatin: implications for DNA repair and genomic integritySirtuins in hematological aging and malignancyInterplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogrammingMetabolism, longevity and epigeneticsSIRTain regulators of premature senescence and accelerated agingSirtuins in Cancer: a Balancing Act between Genome Stability and MetabolismDNA damage and repair in atherosclerosis: current insights and future perspectivesSirtuins, metabolism, and DNA repairMolecular mechanism of extrinsic factors affecting anti-aging of stem cellsSirtuins in epigenetic regulationImpacts on Sirtuin Function and Bioavailability of the Dietary Bioactive Compound DihydrocoumarinCre-mediated stress affects sirtuin expression levels, peroxisome biogenesis and metabolism, antioxidant and proinflammatory signaling pathwaysAcetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and CancerThe promise and perils of HDAC inhibitors in neurodegenerationSIRT6 is required for maintenance of telomere position effect in human cellsSystematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repairDietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cellsBRCA1 and CtIP Are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous RecombinationOxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signalingNuclear DNA damage signalling to mitochondria in ageingOver expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFκB responsesGemcitabine induces poly (ADP-ribose) polymerase-1 (PARP-1) degradation through autophagy in pancreatic cancerNicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from PellagraAn acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms.Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity.SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancerCharacterization of physiological defects in adult SIRT6-/- micePeptides and Pseudopeptides as SIRT6 Deacetylation Inhibitors.SIRT6 promotes DNA repair under stress by activating PARP1Targeted sister chromatid cohesion by Sir2.Immunofluorescence-based methods to monitor DNA end resection.Sirtuins: guardians of mammalian healthspan.Quinolinate Phosphoribosyltransferase is an Antiviral Host Factor Against Hepatitis C Virus Infection.
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P2860
Human SIRT6 promotes DNA end resection through CtIP deacetylation
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@ast
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@en
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@en-gb
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@nl
type
label
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@ast
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@en
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@en-gb
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@nl
prefLabel
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@ast
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@en
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@en-gb
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@nl
P2860
P50
P3181
P356
P1433
P1476
Human SIRT6 promotes DNA end resection through CtIP deacetylation
@en
P2093
Chunaram Choudhary
P2860
P304
P3181
P356
10.1126/SCIENCE.1192049
P407
P577
2010-09-10T00:00:00Z