Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway
about
Targeting Protein-Protein Interactions in the HIF SystemTargeting leukemia stem cells: which pathways drive self-renewal activity in T-cell acute lymphoblastic leukemia?Targeting Oncogenic Mutant p53 for Cancer TherapyProgress toward overcoming hypoxia-induced resistance to solid tumor therapyEpidithiodioxopiperazines. occurrence, synthesis and biogenesisProtein lysine acetylation by p300/CBPLung macrophages contribute to house dust mite driven airway remodeling via HIF-1αRegulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small MoleculesExploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologiesAssessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesisThe impact of O2 availability on human cancerHIF-1α inhibition by siRNA or chetomin in human malignant glioma cells: effects on hypoxic radioresistance and monitoring via CA9 expression.Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertensionEnantioselective total synthesis of plectosphaeroic acid BEnantioselective total syntheses of plectosphaeroic acids B and C.Effects of HIF-1 inhibition by chetomin on hypoxia-related transcription and radiosensitivity in HT 1080 human fibrosarcoma cells.Motor neurons control blood vessel patterning in the developing spinal cordQuiescence of adult oligodendrocyte precursor cells requires thyroid hormone and hypoxia to activate Runx1.Natural product-based inhibitors of hypoxia-inducible factor-1 (HIF-1).A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulationThe F-box protein beta-TrCp1/Fbw1a interacts with p300 to enhance beta-catenin transcriptional activity.Identification of a novel small molecule HIF-1alpha translation inhibitor.Identification of small molecule compounds that inhibit the HIF-1 signaling pathwayTargeting aerobic glycolysis and HIF-1alpha expression enhance imiquimod-induced apoptosis in cancer cells.Inhibition of hypoxia-inducible factor-1alpha (HIF-1alpha) protein synthesis by DNA damage inducing agentsDirect organocatalytic coupling of carboxylated piperazine-2,5-diones with indoles through conjugate addition of carbon nucleophiles to indolenine intermediates.Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditionsEnantioselective organocatalytic alpha-sulfenylation of substituted diketopiperazines.Hypoxia-specific targets in cancer therapy: role of splice variantsIn vivo modulation of hypoxia-inducible signaling by topographical helix mimetics.Development of HIF-1 inhibitors for cancer therapyHypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor.High-throughput screening for modulators of protein-protein interactions: use of photonic crystal biosensors and complementary technologies.Vascular injury involves the overoxidation of peroxiredoxin type II and is recovered by the peroxiredoxin activity mimetic that induces reendothelialization.Targeting protein-protein interactions for therapeutic intervention: a challenge for the future.Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1.Molecular-targeted antitumor agents. 19. Furospongolide from a marine Lendenfeldia sp. sponge inhibits hypoxia-inducible factor-1 activation in breast tumor cells.Epidithiodiketopiperazines (ETPs) exhibit in vitro antiangiogenic and in vivo antitumor activity by disrupting the HIF-1α/p300 complex in a preclinical model of prostate cancer.Marine Natural Products as Inhibitors of Hypoxic Signaling in Tumors.
P2860
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P248
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P2860
Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Small molecule blockade of tra ...... poxia-inducible factor pathway
@ast
Small molecule blockade of tra ...... poxia-inducible factor pathway
@en
Small molecule blockade of tra ...... poxia-inducible factor pathway
@en-gb
Small molecule blockade of tra ...... poxia-inducible factor pathway
@nl
type
label
Small molecule blockade of tra ...... poxia-inducible factor pathway
@ast
Small molecule blockade of tra ...... poxia-inducible factor pathway
@en
Small molecule blockade of tra ...... poxia-inducible factor pathway
@en-gb
Small molecule blockade of tra ...... poxia-inducible factor pathway
@nl
prefLabel
Small molecule blockade of tra ...... poxia-inducible factor pathway
@ast
Small molecule blockade of tra ...... poxia-inducible factor pathway
@en
Small molecule blockade of tra ...... poxia-inducible factor pathway
@en-gb
Small molecule blockade of tra ...... poxia-inducible factor pathway
@nl
P2093
P921
P1433
P1476
Small molecule blockade of tra ...... poxia-inducible factor pathway
@en
P2093
Alexander W Wood
Annelisa Vieira
Beqing Wang
David M Livingston
Dennis S France
Elizabeth A Tanner
Frank Petersen
Hans-Ulrich Naegeli
Jamin Wang
Jennifer Lee
P356
10.1016/J.CCR.2004.06.009
P407
P577
2004-07-01T00:00:00Z