SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
about
Salvianolic acid B prevents epithelial-to-mesenchymal transition through the TGF-beta1 signal transduction pathway in vivo and in vitroIdentification of TGF-beta receptor-1 as a key regulator of carbon nanotube-induced fibrogenesisThe MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoterInteraction with Smad4 is indispensable for suppression of BMP signaling by c-SkiActivin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitorsEndogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cellsEffects of growth differentiation factor 9 on cell cycle regulators and ERK42/44 in human granulosa cell proliferationHEB and E2A function as SMAD/FOXH1 cofactorsNuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-beta signalingPluripotency factors regulate definitive endoderm specification through eomesoderminRequirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells.Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cellsRole of DeltaNp63gamma in epithelial to mesenchymal transitionCritical regulation of TGFbeta signaling by Hsp90TGF-beta1 stimulates human AT1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathwaysNodal signalling is involved in left-right asymmetry in snailsInhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARASkeletal muscle wasting and renewal: a pivotal role of myokine IL-6Peripheral Blood Monocytes as Adult Stem Cells: Molecular Characterization and Improvements in Culture Conditions to Enhance Stem Cell Features and Proliferative PotentialKnowledge Gaps in Rodent Pancreas Biology: Taking Human Pluripotent Stem Cell-Derived Pancreatic Beta Cells into Our Own HandsGood and bad sides of TGFβ-signaling in myocardial infarctionMechanisms of bone anabolism regulated by statinsNegative Regulation of TGFβ Signaling by Stem Cell Antigen-1 Protects against Ischemic Acute Kidney InjuryA novel TGFβ modulator that uncouples R-Smad/I-Smad-mediated negative feedback from R-Smad/ligand-driven positive feedbackInhibition of TGFβ signaling increases direct conversion of fibroblasts to induced cardiomyocytesHuman Cerberus prevents nodal-receptor binding, inhibits nodal signaling, and suppresses nodal-mediated phenotypesNodal dependent differential localisation of dishevelled-2 demarcates regions of differing cell behaviour in the visceral endodermIntrathecal bone marrow stromal cells inhibit neuropathic pain via TGF-β secretion.TGFbeta1 stimulates the over-production of white matter astrocytes from precursors of the "brain marrow" in a rodent model of neonatal encephalopathyBmp and nodal independently regulate lefty1 expression to maintain unilateral nodal activity during left-right axis specification in zebrafishEarly activation of FGF and nodal pathways mediates cardiac specification independently of Wnt/beta-catenin signalingAncestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinodermGeneration of trophoblast stem cells from rabbit embryonic stem cells with BMP4Structural basis for specificity of TGFβ family receptor small molecule inhibitorsA new class of small molecule inhibitor of BMP signalingComplexities of TGF-β targeted cancer therapy.Activin receptor-like kinases: a diverse family playing an important role in cancerBrachyury cooperates with Wnt/β-catenin signalling to elicit primitive-streak-like behaviour in differentiating mouse embryonic stem cellsExpression and regulation of the osteoarthritis-associated protein asporinFibulin-5 gene expression in human lung fibroblasts is regulated by TGF-beta and phosphatidylinositol 3-kinase activity
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P248
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P2860
SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@ast
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@en
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@en-gb
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@nl
type
label
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@ast
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@en
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@en-gb
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@nl
prefLabel
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@ast
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@en
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@en-gb
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@nl
P2093
P921
P3181
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P1476
SB-431542 is a potent and spec ...... receptors ALK4, ALK5, and ALK7
@en
P2093
Alastair D Reith
Francisco J Nicolás
James F Callahan
John D Harling
Laramie M Gaster
Nicholas J Laping
P3181
P356
10.1124/MOL.62.1.65
P407
P577
2002-07-01T00:00:00Z