ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation
about
Cell cycle-dependent chromatin shuttling of HBO1-JADE1 histone acetyl transferase (HAT) complex.Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperoneStructural insights into recognition of acetylated histone ligands by the BRPF1 bromodomainING2 as a novel mediator of transforming growth factor-beta-dependent responses in epithelial cellsTargeted disruption of Ing2 results in defective spermatogenesis and development of soft-tissue sarcomasING2 controls the progression of DNA replication forks to maintain genome stabilityMolecular architecture of quartet MOZ/MORF histone acetyltransferase complexesThe inhibitor of growth protein 5 (ING5) depends on INCA1 as a co-factor for its antiproliferative effectsMOZ increases p53 acetylation and premature senescence through its complex formation with PMLSolution structure and NMR characterization of the binding to methylated histone tails of the plant homeodomain finger of the tumour suppressor ING4Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF)ING2 PHD domain links histone H3 lysine 4 methylation to active gene repressionHECT ubiquitin ligase Smurf1 targets the tumor suppressor ING2 for ubiquitination and degradationING4 inhibits the translation of proto-oncogene MYC by interacting with AUF1MOZ and MORF, two large MYSTic HATs in normal and cancer stem cellsCovalent histone modifications--miswritten, misinterpreted and mis-erased in human cancersMutations in KAT6B, encoding a histone acetyltransferase, cause Genitopatellar syndromeNutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescenceStudying epigenetic complexes and their inhibitors with the proteomics toolboxThe interplay of histone modifications - writers that readKeep-ING balance: tumor suppression by epigenetic regulationThe Mcm2-7 replicative helicase: a promising chemotherapeutic targetAltered histone modifications in gliomasING1 and 5-azacytidine act synergistically to block breast cancer cell growthYng1 PHD Finger Binding to H3 Trimethylated at K4 Promotes NuA3 HAT Activity at K14 of H3 and Transcription at a Subset of Targeted ORFsMolecular Basis of Histone H3K4me3 Recognition by ING4Histone H3K4me3 Binding Is Required for the DNA Repair and Apoptotic Activities of ING1 Tumor SuppressorThe crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptideING4 Mediates Crosstalk between Histone H3 K4 Trimethylation and H3 Acetylation to Attenuate Cellular TransformationSolution structure of a novel zinc finger motif in the SAP30 polypeptide of the Sin3 corepressor complex and its potential role in nucleic acid recognitionHaematopoietic malignancies caused by dysregulation of a chromatin-binding PHD fingerFunctional impact of cancer-associated mutations in the tumor suppressor protein ING4Structure of the 30-kDa Sin3-associated Protein (SAP30) in Complex with the Mammalian Sin3A Corepressor and Its Role in Nucleic Acid BindingCrystal Structure of Inhibitor of Growth 4 (ING4) Dimerization Domain Reveals Functional Organization of ING Family of Chromatin-binding ProteinsThe double PHD finger domain of MOZ/MYST3 induces -helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modificationCombinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcriptionThe Yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone H3.A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.NuA4-dependent acetylation of nucleosomal histones H4 and H2A directly stimulates incorporation of H2A.Z by the SWR1 complex.
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P2860
ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation
description
2006 nî lūn-bûn
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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
@zh-hk
2006年論文
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2006年論文
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2006年论文
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name
ING tumor suppressor proteins ...... me expression and perpetuation
@ast
ING tumor suppressor proteins ...... me expression and perpetuation
@en
ING tumor suppressor proteins ...... me expression and perpetuation
@en-gb
ING tumor suppressor proteins ...... me expression and perpetuation
@nl
type
label
ING tumor suppressor proteins ...... me expression and perpetuation
@ast
ING tumor suppressor proteins ...... me expression and perpetuation
@en
ING tumor suppressor proteins ...... me expression and perpetuation
@en-gb
ING tumor suppressor proteins ...... me expression and perpetuation
@nl
prefLabel
ING tumor suppressor proteins ...... me expression and perpetuation
@ast
ING tumor suppressor proteins ...... me expression and perpetuation
@en
ING tumor suppressor proteins ...... me expression and perpetuation
@en-gb
ING tumor suppressor proteins ...... me expression and perpetuation
@nl
P2093
P3181
P1433
P1476
ING tumor suppressor proteins ...... me expression and perpetuation
@en
P2093
Anne-Julie Landry
Jacques Côté
Mukta Ullah
Valérie Côté
William S Lane
William Selleck
Xiang-Jiao Yang
P3181
P356
10.1016/J.MOLCEL.2005.12.007
P407
P577
2006-01-06T00:00:00Z