Unusual transient- and steady-state kinetic behavior is predicted by the kinetic scheme operational for recombinant human dihydrofolate reductase
about
Human endothelial dihydrofolate reductase low activity limits vascular tetrahydrobiopterin recyclingThe extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intakeUnderstanding bistability in complex enzyme-driven reaction networksCorrelations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes † ‡Crystal Structure of Bacillus anthracis Dihydrofolate Reductase with the Dihydrophthalazine-Based Trimethoprim Derivative RAB1 Provides a Structural Explanation of Potency and SelectivityKinetic and Structural Characterization of Dihydrofolate Reductase from Streptococcus pneumoniaeFunctional significance of evolving protein sequence in dihydrofolate reductase from bacteria to humansDivergent evolution of protein conformational dynamics in dihydrofolate reductase.Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase.Kinetic and chemical mechanism of the dihydrofolate reductase from Mycobacterium tuberculosisInsights into the slow-onset tight-binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2-f] quinazoline-1,3-diamine and its derivatives as novel tight-binding inhibitors.Identification of endogenous ligands bound to bacterially expressed human and E. coli dihydrofolate reductase by 2D NMR.The Effect of Protein Mass Modulation on Human Dihydrofolate Reductase.Side chain conformational averaging in human dihydrofolate reductase.Two parallel pathways in the kinetic sequence of the dihydrofolate reductase from Mycobacterium tuberculosisHydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima.
P2860
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P2860
Unusual transient- and steady-state kinetic behavior is predicted by the kinetic scheme operational for recombinant human dihydrofolate reductase
description
1990 nî lūn-bûn
@nan
1990 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Unusual transient- and steady- ...... human dihydrofolate reductase
@ast
Unusual transient- and steady- ...... human dihydrofolate reductase
@en
Unusual transient- and steady- ...... human dihydrofolate reductase
@en-gb
Unusual transient- and steady- ...... human dihydrofolate reductase
@nl
type
label
Unusual transient- and steady- ...... human dihydrofolate reductase
@ast
Unusual transient- and steady- ...... human dihydrofolate reductase
@en
Unusual transient- and steady- ...... human dihydrofolate reductase
@en-gb
Unusual transient- and steady- ...... human dihydrofolate reductase
@nl
prefLabel
Unusual transient- and steady- ...... human dihydrofolate reductase
@ast
Unusual transient- and steady- ...... human dihydrofolate reductase
@en
Unusual transient- and steady- ...... human dihydrofolate reductase
@en-gb
Unusual transient- and steady- ...... human dihydrofolate reductase
@nl
P2093
P1476
Unusual transient- and steady- ...... human dihydrofolate reductase
@en
P2093
Appleman JR
Blakley RL
Delcamp TJ
Freisheim JH
Prendergast NJ
P304
P407
P577
1990-02-01T00:00:00Z