Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen
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Guidelines for the use and interpretation of assays for monitoring autophagyGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Neuritogenic militarinone-inspired 4-hydroxypyridones target the stress pathway kinase MAP4K4Neurite outgrowth of mature retinal ganglion cells and PC12 cells requires activity of CK1δ and CK1εDevelopment of an intracellularly acting inhibitory peptide selective for PKN.A cell spot microarray method for production of high density siRNA transfection microarrays.Applications of high content screening in life science researchGenerating 'omic knowledge': the role of informatics in high content screeningIdentification of small molecule inhibitors of neurite loss induced by Aβ peptide using high content screening.Chemical interrogation of the neuronal kinome using a primary cell-based screening assay.High-content siRNA screening for target identification and validation.A loss-of-function screen for phosphatases that regulate neurite outgrowth identifies PTPN12 as a negative regulator of TrkB tyrosine phosphorylation.miR-106a-5p inhibits the proliferation and migration of astrocytoma cells and promotes apoptosis by targeting FASTKCoordinate regulation of mature dopaminergic axon morphology by macroautophagy and the PTEN signaling pathway.Adaptations to a subterranean environment and longevity revealed by the analysis of mole rat genomes.JNK isoforms differentially regulate neurite growth and regeneration in dopaminergic neurons in vitro.A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiationDiscovery of a novel ROCK2 inhibitor with anti-migration effects via docking and high-content drug screening.Phenotypic Screening of Small-Molecule Inhibitors: Implications for Therapeutic Discovery and Drug Target Development in Traumatic Brain Injury.Adenosine monophosphate-activated protein kinase overactivation leads to accumulation of α-synuclein oligomers and decrease of neurites.Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturationRational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth.Map4k4 Signaling Nodes in Metabolic and Cardiovascular DiseasesAll-you-can-eat: autophagy in neurodegeneration and neuroprotection.LRRK2 in Parkinson's disease: function in cells and neurodegeneration.Nuclear and cytosolic JNK signalling in neurons.In vitro models of axon regeneration.Mutation of ataxia-telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia.Neoteny, Prolongation of Youth: From Naked Mole Rats to "Naked Apes" (Humans).Interference with the PTEN-MAST2 interaction by a viral protein leads to cellular relocalization of PTEN.Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line.High content screening of cortical neurons identifies novel regulators of axon growth.Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis.Kinase/phosphatase overexpression reveals pathways regulating hippocampal neuron morphology.The mTOR Substrate S6 Kinase 1 (S6K1) Is a Negative Regulator of Axon Regeneration and a Potential Drug Target for Central Nervous System Injury.Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration.
P2860
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P2860
Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Identification of new kinase c ...... nction RNA interference screen
@ast
Identification of new kinase c ...... nction RNA interference screen
@en
Identification of new kinase c ...... nction RNA interference screen
@en-gb
Identification of new kinase c ...... nction RNA interference screen
@nl
type
label
Identification of new kinase c ...... nction RNA interference screen
@ast
Identification of new kinase c ...... nction RNA interference screen
@en
Identification of new kinase c ...... nction RNA interference screen
@en-gb
Identification of new kinase c ...... nction RNA interference screen
@nl
prefLabel
Identification of new kinase c ...... nction RNA interference screen
@ast
Identification of new kinase c ...... nction RNA interference screen
@en
Identification of new kinase c ...... nction RNA interference screen
@en-gb
Identification of new kinase c ...... nction RNA interference screen
@nl
P2093
P2860
P921
P356
P1476
Identification of new kinase c ...... nction RNA interference screen
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.CDD.4402258
P407
P50
P577
2007-11-16T00:00:00Z
P5875
P6179
1031951082