Role of steroid 11 beta-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humans
about
Structural insights into aldosterone synthase substrate specificity and targeted inhibitionThe molecular biology, biochemistry, and physiology of human steroidogenesis and its disordersA novel genetic locus for low renin hypertension: familial hyperaldosteronism type II maps to chromosome 7 (7p22)Adrenal Mitochondria and Steroidogenesis: From Individual Proteins to Functional Protein AssembliesBinding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterolsRole of ALADIN in human adrenocortical cells for oxidative stress response and steroidogenesis3-Pyridyl substituted aliphatic cycles as CYP11B2 inhibitors: aromaticity abolishment of the core significantly increased selectivity over CYP1A2Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells.Overexpression and Knockdown of Hypoxia-Inducible Factor 1 Disrupt the Expression of Steroidogenic Enzyme Genes and Early Embryonic Development in Zebrafish.Adrenal CYP11B1/2 expression in primary aldosteronism: immunohistochemical analysis using novel monoclonal antibodies.Noncanonical mechanisms to regulate nuclear receptor signaling.Glucocorticoid-suppressible hyperaldosteronism and adrenal tumors occurring in a single French pedigree.A role for the NGFI-B family in adrenal zonation and adrenocortical disease.Maternal Cortisol Mediates Hypothalamus-Pituitary-Interrenal Axis Development in Zebrafish.Dihydrotestosterone stimulates aldosterone secretion by H295R human adrenocortical cells.QSAR of cytochrome inhibitors.Development of monoclonal antibodies against human CYP11B1 and CYP11B2.The potential of targeting CYP11B.Interventional procedures and future drug therapy for hypertension.Immunohistochemistry of aldosterone synthase leads the way to the pathogenesis of primary aldosteronism.Regulation of adrenal aldosterone production by serine protease prostasin.Involvement of an AP-1 complex in zone-specific expression of the CYP11B1 gene in the rat adrenal cortex.Haplotype association and synergistic effect of human aldosterone synthase (CYP11B2) gene polymorphisms causing susceptibility to essential hypertension in Indian patients.Calcium regulates human CYP11B2 transcription.Cloning of CYP11B1 and CYP11B2 from normal human adrenal and their functional expression in COS-7 and V79 Chinese hamster cells.Human adrenal CYP11B1: localization by in situ-hybridization and functional expression in cell cultures.Light and electron microscopic immunohistochemistry of the localization of adrenal steroidogenic enzymes.Mutation T318M in the CYP11B2 gene encoding P450c11AS (aldosterone synthase) causes corticosterone methyl oxidase II deficiency.A novel haplotype of low-frequency variants in the aldosterone synthase gene among northern Han Chinese with essential hypertension.Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice.Polymorphisms in CYP11B2 and CYP11B1 genes associated with primary hyperaldosteronism.Exploring QSAR for CYP11B2 binding affinity and CYP11B2/CYP11B1 selectivity of diverse functional compounds using GFA and G/PLS techniques.Role of hypothalamic-pituitary axis in EGF action on maturation of adrenal gland in fetal rhesus monkey in vivo.Beyond cancer genes: colorectal cancer as robust intrinsic states formed by molecular interactions.Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells.Neglected issues concerning teaching human adrenal steroidogenesis in popular biochemistry textbooks.A Novel Somatic Deletion Mutation of ATP2B3 in Aldosterone-Producing Adenoma.DIAGNOSIS OF ENDOCRINE DISEASE: 18-Oxocortisol and 18-hydroxycortisol: is there clinical utility of these steroids?Pharmacophore Modeling and in Silico/in Vitro Screening for Human Cytochrome P450 11B1 and Cytochrome P450 11B2 Inhibitors.CYP11B1 oxidises 11DCORT
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Role of steroid 11 beta-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humans
description
1992 nî lūn-bûn
@nan
1992 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@ast
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@en
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@en-gb
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@nl
type
label
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@ast
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@en
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@en-gb
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@nl
prefLabel
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@ast
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@en
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@en-gb
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@nl
P2093
P2860
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P3181
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P1476
Role of steroid 11 beta-hydrox ...... d mineralocorticoids in humans
@en
P2093
K Miyahara
Y Ichikawa
Y Mitsuuchi
Y Yokoyama
P2860
P304
P3181
P356
10.1073/PNAS.89.4.1458
P407
P577
1992-02-01T00:00:00Z