A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation
about
Progressive, transgenerational changes in offspring phenotype and epigenotype following nutritional transitionThe histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cellsStructure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylationDNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNAModifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in DiseaseStructural and functional coordination of DNA and histone methylationThe de novo DNA methyltransferase DNMT3A in development and cancerMPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9aStructural insight into autoinhibition and histone H3-induced activation of DNMT3ADNA methyltransferases and methyl-binding proteins of mammalsThe lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylationDnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencingLsh is involved in de novo methylation of DNASynergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and NanogThe PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatinEssential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprintingAssociation of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatinG9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcriptionPhenotypic switching induced by damaged matrix is associated with DNA methyltransferase 3A (DNMT3A) activity and nuclear localization in smooth muscle cells (SMC)Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted lociEpigenetic Guardian: A Review of the DNA Methyltransferase DNMT3A in Acute Myeloid Leukaemia and Clonal Haematopoiesis.DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons.A gene expression signature shared by human mature oocytes and embryonic stem cells.Identification of DNA methyltransferase 3a as a T cell receptor-induced regulator of Th1 and Th2 differentiation.Introduction--Epiphanies in epigenetics.2i Maintains a Naive Ground State in ESCs through Two Distinct Epigenetic Mechanisms.DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo.Experimental approaches to the study of epigenomic dysregulation in ageingCoordinated chromatin control: structural and functional linkage of DNA and histone methylation.Epigenetic genes and emotional reactivity to daily life events: a multi-step gene-environment interaction study.Establishment of a conditional transgenic system using the 2A peptide in the female mouse germline.Expression patterns and miRNA regulation of DNA methyltransferases in chicken primordial germ cellsRescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities.The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation.Comparison of epigenetic mediator expression and function in mouse and human embryonic blastomeresStable methylation at promoters distinguishes epiblast stem cells from embryonic stem cells and the in vivo epiblasts.Molecular and enzymatic profiles of mammalian DNA methyltransferases: structures and targets for drugs.Epigenetic memory: the Lamarckian brainA role for epigenetics in hearing: Establishment and maintenance of auditory specific gene expression patterns.DNMT3A in haematological malignancies.
P2860
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P2860
A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@ast
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@en
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@en-gb
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@nl
type
label
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@ast
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@en
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@en-gb
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@nl
prefLabel
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@ast
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@en
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@en-gb
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@nl
P2093
P2860
P921
P3181
P356
P1476
A novel Dnmt3a isoform produce ...... ith active de novo methylation
@en
P2093
Shaoping Xie
Taiping Chen
Yoshihide Ueda
P2860
P304
P3181
P356
10.1074/JBC.M205312200
P407
P577
2002-10-11T00:00:00Z