The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins

The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins

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http://www.wikidata.org/entity/Q24303582
ADAM9 is highly expressed in renal cell cancer and is associated with tumour progression.The mojastin mutant Moj-DM induces apoptosis of the human melanoma SK-Mel-28, but not the mutant Moj-NN nor the non-mutated recombinant Moj-WN.Functional analysis of a recombinant PIII-SVMP, GST-acocostatin; an apoptotic inducer of HUVEC and HeLa, but not SK-Mel-28 cellsADAM9 is a novel product of polymorphonuclear neutrophils: regulation of expression and contributions to extracellular matrix protein degradation during acute lung injury.Recombinant rubistatin (r-Rub), an MVD disintegrin, inhibits cell migration and proliferation, and is a strong apoptotic inducer of the human melanoma cell line SK-Mel-28.Secreted and membrane-bound isoforms of protease ADAM9 have opposing effects on breast cancer cell migration.Gene expression profiles of the NCI-60 human tumor cell lines define molecular interaction networks governing cell migration processesIn vivo targeting of ADAM9 gene expression using lentivirus-delivered shRNA suppresses prostate cancer growth by regulating REG4 dependent cell cycle progressionLoss of the metalloprotease ADAM9 leads to cone-rod dystrophy in humans and retinal degeneration in mice.The emerging role of matrix metalloproteases of the ADAM family in male germ cell apoptosis.ADAM-family metalloproteinases in lung inflammation: potential therapeutic targets.High expression of a disintegrin and metalloproteinase-9 predicts a shortened survival time in completely resected stage I non-small cell lung cancer.Platelet Integrins in Tumor Metastasis: Do They Represent a Therapeutic Target?ADAM9 is present at endothelial cell - cell junctions and regulates monocyte - endothelial transmigration.Loss of ADAM9 expression impairs β1 integrin endocytosis, focal adhesion formation and cancer cell migration.MicroRNA-126 inhibits proliferation and metastasis in prostate cancer via regulation of ADAM9.
P2860

The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins

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http://www.wikidata.org/entity/Q24303582
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
@ast
The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
@en
The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
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The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
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type
label
The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
@ast
The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
@en
The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
@en-gb
The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
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prefLabel
The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
@ast
The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
@en
The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
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The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932