ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
about
The transcription factor p53: not a repressor, solely an activatorMechanism of ASC-mediated apoptosis: bid-dependent apoptosis in type II cellsUV irradiation resistance-associated gene suppresses apoptosis by interfering with BAX activationViral apoptosis is induced by IRF-3-mediated activation of BaxCaspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiationCDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent mannerKnockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neuronsLoss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosisNLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species productionMolecular mechanisms of inflammasome activation during microbial infectionsStructure and Interdomain Dynamics of Apoptosis-associated Speck-like Protein Containing a CARD (ASC)Fatal liaisons of p53 with Bax and BakTIP30 regulates apoptosis-related genes in its apoptotic signal transduction pathwayThe PYRIN domain in signal transductionActivation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domainSynergism and rules from combination of Baicalin, Jasminoidin and Desoxycholic acid in refined Qing Kai Ling for treat ischemic stroke mice modelPoly(ADP-ribose) polymerase-1 protects neurons against apoptosis induced by oxidative stressInhibition of mitochondrial respiration by nitric oxide rapidly stimulates cytoprotective GLUT3-mediated glucose uptake through 5'-AMP-activated protein kinaseInhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathwayStra6, a retinoic acid-responsive gene, participates in p53-induced apoptosis after DNA damage.Non-cell-autonomous tumor suppression by p53.Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway.The PYRIN connection: novel players in innate immunity and inflammation.Bax contains two functional mitochondrial targeting sequences and translocates to mitochondria in a conformational change- and homo-oligomerization-driven process.Intrinsic response of thoracic propriospinal neurons to axotomy.Silencing of TMS1/ASC promotes resistance to anoikis in breast epithelial cells.Long descending cervical propriospinal neurons differ from thoracic propriospinal neurons in response to low thoracic spinal injuryTNF-α contributes to caspase-3 independent apoptosis in neuroblastoma cells: role of NFATThe helix-loop-helix transcription factor TWIST is dysregulated in myelodysplastic syndromes.PYNOD, a novel Apaf-1/CED4-like protein is an inhibitor of ASC and caspase-1.Inhibition of pluripotent stem cell-derived teratoma formation by small moleculesGenomic analysis reveals pre- and postchallenge differences in a rhesus macaque AIDS vaccine trial: insights into mechanisms of vaccine efficacyApoptosis-associated speck-like protein (ASC) controls Legionella pneumophila infection in human monocytes.An updated view on the structure and function of PYRIN domains.Asc-dependent and independent mechanisms contribute to restriction of legionella pneumophila infection in murine macrophages.NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases.A new 'Linc' between noncoding RNAs and blood development.Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation.Correlation between promoter methylation of p14(ARF), TMS1/ASC, and DAPK, and p53 mutation with prognosis in cholangiocarcinomaHeat stress induced apoptosis is triggered by transcription-independent p53, Ca(2+) dyshomeostasis and the subsequent Bax mitochondrial translocation.
P2860
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P2860
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@ast
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@en
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@en-gb
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@nl
type
label
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@ast
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@en
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@en-gb
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@nl
prefLabel
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@ast
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@en
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@en-gb
ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@nl
P2093
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P3181
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ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway
@en
P2093
Junji Sagara
Keiichi I Nakayama
Stuart A Aaronson
Takao Ohtsuka
P2860
P2888
P304
P3181
P356
10.1038/NCB1087
P407
P577
2004-01-18T00:00:00Z
P6179
1004788653