STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
about
Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activationPI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins.STIM1 couples to ORAI1 via an intramolecular transition into an extended conformationAtomic force microscopy (AFM) imaging suggests that stromal interaction molecule 1 (STIM1) binds to Orai1 with sixfold symmetryRestricted epithelial proliferation by lacritin via PKCalpha-dependent NFAT and mTOR pathwaysStore-independent activation of Orai1 by SPCA2 in mammary tumorsSTIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levelsAgonist-activated Ca2+ influx occurs at stable plasma membrane and endoplasmic reticulum junctionsA protease-independent function for SPPL3 in NFAT activationA novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cellsUbiquilin 1 interacts with Orai1 to regulate calcium mobilizationThe kinase Syk as an adaptor controlling sustained calcium signalling and B-cell developmentSTIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entryJunctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1)STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membraneAmplification of CRAC current by STIM1 and CRACM1 (Orai1)Modulation of STIM1 and capacitative Ca2+ entry by the endoplasmic reticulum luminal oxidoreductase ERp57INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contactsSTIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channelsGenome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activityGlial cells physiologically modulate clock neurons and circadian behavior in a calcium-dependent mannerCalcium signaling in mammalian egg activation and embryo development: the influence of subcellular localizationHuman muscle economy myoblast differentiation and excitation-contraction coupling use the same molecular partners, STIM1 and STIM2The roles of cyclin A2, B1, and B2 in early and late mitotic eventsDynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel componentsSTIM proteins: dynamic calcium signal transducersNew developments in mast cell biologyDual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and toleranceSTIM1 heteromultimerizes TRPC channels to determine their function as store-operated channelsT cell activationCoupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum.An EF hand mutation in Stim1 causes premature platelet activation and bleeding in miceCa2+ toxicity and mitochondrial damage in acute pancreatitis: translational overviewSTIM and Orai1 Variants in Store-Operated Calcium EntryThe functions of TRPP2 in the vascular systemThe role of STIM and ORAI proteins in phagocytic immune cellsThe different facets of organelle interplay-an overview of organelle interactionsSOCE and cancer: Recent progress and new perspectives
P2860
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P2860
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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name
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@ast
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@en
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@en-gb
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@nl
type
label
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@ast
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@en
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@en-gb
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@nl
prefLabel
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@ast
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@en
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@en-gb
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@nl
P2093
P2860
P921
P3181
P1433
P1476
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
@en
P2093
James E Ferrell
Jason W Myers
Joshua T Jones
Man Lyang Kim
Tobias Meyer
Won Do Heo
P2860
P304
P3181
P356
10.1016/J.CUB.2005.05.055
P407
P577
2005-07-12T00:00:00Z