Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
about
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolusPlk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1Plk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentationDetermination of the Plk4/Sak consensus phosphorylation motif using peptide spots arraysPlk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppressionCalcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cellsDistinct pools of cdc25C are phosphorylated on specific TP sites and differentially localized in human mitotic cellsPhosphorylation of synucleins by members of the Polo-like kinase family.Polo-box domain: a versatile mediator of polo-like kinase function.A PREVIOUSLY UNKNOWN UNIQUE CHALLENGE FOR INHIBITORS OF SYK ATP-BINDING SITE: ROLE OF SYK AS A CELL CYCLE CHECKPOINT REGULATORThe uncovering of a novel regulatory mechanism for PLD2: formation of a ternary complex with protein tyrosine phosphatase PTP1B and growth factor receptor-bound protein GRB2.From Plk1 to Plk5: functional evolution of polo-like kinasesCdk5 promotes DNA replication stress checkpoint activation through RPA-32 phosphorylation, and impacts on metastasis free survival in breast cancer patients.Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression.Computational modeling of signaling pathways mediating cell cycle checkpoint control and apoptotic responses to ionizing radiation-induced DNA damage.Phosphatases and kinases regulating CDC25 activity in the cell cycle: clinical implications of CDC25 overexpression and potential treatment strategiesCytoskeletal architecture and cell motility remain unperturbed in mouse embryonic fibroblasts from Plk3 knockout mice.Opticin, a small leucine-rich proteoglycan, is uniquely expressed and translocated to the nucleus of chronic lymphocytic leukemia cells.Beyond ATM: the protein kinase landscape of the DNA damage response.Polo-like kinases: structural variations lead to multiple functions.A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor.The role of Plk3 in oncogenesis.Abortive cell cycle events in the brains of scrapie-infected hamsters with remarkable decreases of PLK3/Cdc25C and increases of PLK1/cyclin B1.Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets.Bromelain inhibits nuclear factor kappa-B translocation, driving human epidermoid carcinoma A431 and melanoma A375 cells through G(2)/M arrest to apoptosis.Phosphorylation of CDC25C at S263 controls its intracellular localisation.Roles of Polo-like kinase 3 in suppressing tumor angiogenesis.TP53 Regulates Transcription of Cell Cycle GenesTP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertainPLK4: a link between centriole biogenesis and cancer.PLK3 phosphorylates CDC25CThe Ste20-like kinase SLK is required for cell cycle progression through G2.
P2860
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P2860
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
description
2004 nî lūn-bûn
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2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
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2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
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name
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@ast
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@en
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@en-gb
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@nl
type
label
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@ast
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@en
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@en-gb
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@nl
prefLabel
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@ast
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@en
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@en-gb
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@nl
P2093
P2860
P921
P356
P1433
P1476
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
@en
P2093
David L Myer
El Mustapha Bahassi
Peter J Stambrook
Robert F Hennigan
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207425
P407
P577
2004-04-08T00:00:00Z
P5875
P6179
1041860136