RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
about
CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage responseHERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomesUbiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombinationThe proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break responseThe AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaksA cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repairThe E3 ligase RNF8 regulates KU80 removal and NHEJ repairUMI, a novel RNF168 ubiquitin binding domain involved in the DNA damage signaling pathwayBAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose) activation, ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sitesUbiquitin-activating enzyme UBA1 is required for cellular response to DNA damageHuman RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaksPRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitryDNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc fingerRNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AXATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaksBBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage responseDNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-linksA genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegiaRing finger protein RNF169 antagonizes the ubiquitin-dependent signaling cascade at sites of DNA damageThe histone demethylase LSD1/KDM1A promotes the DNA damage responseMultiple roles of ATM in monitoring and maintaining DNA integrityDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsMammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaksBMI1-mediated histone ubiquitylation promotes DNA double-strand break repairMolecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylationBMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repairUbc13: the Lys63 ubiquitin chain building machineWriters, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break RepairReal Estate in the DNA Damage Response: Ubiquitin and SUMO Ligases Home in on DNA Double-Strand BreaksRole of Deubiquitinating Enzymes in DNA RepairA Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage ResponseFine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at workFunctional Role of NBS1 in Radiation Damage Response and Translesion DNA SynthesisPR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcriptionProtein degradation and the stress response53BP1: pro choice in DNA repairBRCA1, a 'complex' protein involved in the maintenance of genomic stabilityDNA DSB repair pathway choice: an orchestrated handover mechanismShedding light on filovirus infection with high-content imaging
P2860
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P2860
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@ast
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@en
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@en-gb
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@nl
type
label
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@ast
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@en
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@en-gb
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@nl
prefLabel
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@ast
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@en
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@en-gb
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@nl
P2093
P50
P3181
P1433
P1476
RNF168 binds and amplifies ubi ...... ccumulation of repair proteins
@en
P2093
Carsten Doil
Niels Mailand
Patrice Menard
P304
P3181
P356
10.1016/J.CELL.2008.12.041
P407
P50
P577
2009-02-06T00:00:00Z