ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
about
MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascadesRecognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccinationDENV inhibits type I IFN production in infected cells by cleaving human STINGSingle nucleotide polymorphisms of human STING can affect innate immune response to cyclic dinucleotidesDengue virus targets the adaptor protein MITA to subvert host innate immunityMitochondrial dynamics regulate the RIG-I-like receptor antiviral pathwayHepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunityIRF7: activation, regulation, modification and functionIFI16 is an innate immune sensor for intracellular DNAPCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4Cyclic di-GMP sensing via the innate immune signaling protein STINGAncient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.STING is a direct innate immune sensor of cyclic di-GMPAtg9a controls dsDNA-driven dynamic translocation of STING and the innate immune responseAutophagy in innate recognition of pathogens and adaptive immunityInterplay between Inflammation and Cellular Stress Triggered by Flaviviridae VirusesSpecies-specific detection of the antiviral small-molecule compound CMA by STINGStructure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate ImmunityStructural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP BindingStructure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAACyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced OligomerizationThe structural basis for the sensing and binding of cyclic di-GMP by STINGCrystal structures of STING protein reveal basis for recognition of cyclic di-GMPInnate immune detection of microbial nucleic acids.DNA sensor cGAS-mediated immune recognitionInnate immune recognition of DNA: A recent historyRat and human STINGs profile similarly towards anticancer/antiviral compoundsCytoplasmic DNA innate immune pathwaysInnate immune pattern recognition: a cell biological perspectiveInnate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responsesViral evasion of intracellular DNA and RNA sensingIdentification and characterization of phosphodiesterases that specifically degrade 3'3'-cyclic GMP-AMPThe helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune responseTRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STINGCharacterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging AlphavirusesRIOK3 is an adaptor protein required for IRF3-mediated antiviral type I interferon productionNLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STINGNonspecific DNA Binding of cGAS N Terminus Promotes cGAS Activation.RNF26 temporally regulates virus-triggered type I interferon induction by two distinct mechanismsA Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses.
P2860
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P248
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P2860
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@ast
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@en
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@en-gb
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@nl
type
label
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@ast
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@en
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@en-gb
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@nl
prefLabel
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@ast
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@en
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@en-gb
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@nl
P2093
P2860
P921
P3181
P356
P1476
ERIS, an endoplasmic reticulum ...... signaling through dimerization
@en
P2093
Danying Chen
Fuping You
Huihui Chen
Wenxiang Sun
Xiang Zhou
Zhengfan Jiang
Zhonghe Zhai
P2860
P304
P3181
P356
10.1073/PNAS.0900850106
P407
P50
P577
2009-05-26T00:00:00Z