Anaplastic lymphoma kinase: signalling in development and disease
about
ALK Signaling and Target Therapy in Anaplastic Large Cell LymphomaAnaplastic thyroid cancers harbor novel oncogenic mutations of the ALK geneCrizotinib: from discovery to accelerated development to front-line treatmentAnticancer mechanisms of cannabinoidsThe distinctive nature of adenocarcinoma of the lungMolecular testing in lung cancer in the era of precision medicineEmerging importance of ALK in neuroblastomaMidkine in host defenceThe pivotal role of pathology in the management of lung cancerCrystal structure of the ALK (anaplastic lymphoma kinase) catalytic domainThe R1275Q Neuroblastoma Mutant and Certain ATP-competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma KinaseMolecular pathology of lung cancer: key to personalized medicine.Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor.ALK mutations conferring differential resistance to structurally diverse ALK inhibitors.Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma.Focal DNA copy number changes in neuroblastoma target MYCN regulated genesMolecular pathogenesis of peripheral neuroblastic tumorsThe Structural Characterization of Tumor Fusion Genes and ProteinsALK and NSCLC: Targeted therapy with ALK inhibitorsInternalization and down-regulation of the ALK receptor in neuroblastoma cell lines upon monoclonal antibodies treatmentAnaplastic lymphoma kinase activates the small GTPase Rap1 via the Rap1-specific GEF C3G in both neuroblastoma and PC12 cellsGenome-wide association study of the child behavior checklist dysregulation profileIntegrative Pathway Analysis Using Graph-Based Learning with Applications to TCGA Colon and Ovarian DataEast meets West: ethnic differences in epidemiology and clinical behaviors of lung cancer between East Asians and Caucasians.PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma.Hyperactivation of Alk induces neonatal lethality in knock-in AlkF1178L miceRole of the p55-gamma subunit of PI3K in ALK-induced cell migration: RNAi-based selection of cell migration regulatorsAberrant anaplastic lymphoma kinase activity induces a p53 and Rb-dependent senescence-like arrest in the absence of detectable p53 stabilizationIntegrating in silico prediction methods, molecular docking, and molecular dynamics simulation to predict the impact of ALK missense mutations in structural perspectiveAn evolutionary conserved role for anaplastic lymphoma kinase in behavioral responses to ethanol.Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expressionThe receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning.ALK-activating homologous mutations in LTK induce cellular transformation.The preclinical profile of crizotinib for the treatment of non-small-cell lung cancer and other neoplastic disorders.Initial solid tumor testing (stage 1) of AZD1480, an inhibitor of Janus kinases 1 and 2 by the pediatric preclinical testing program.The Drosophila midkine/pleiotrophin homologues Miple1 and Miple2 affect adult lifespan but are dispensable for alk signaling during embryonic gut formation.Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome.Inhibition of ALK, PI3K/MEK, and HSP90 in murine lung adenocarcinoma induced by EML4-ALK fusion oncogeneAnaplastic lymphoma kinase is required for neurogenesis in the developing central nervous system of zebrafish.A time-resolved luminescence biosensor assay for anaplastic lymphoma kinase (ALK) activity.
P2860
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P2860
Anaplastic lymphoma kinase: signalling in development and disease
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Anaplastic lymphoma kinase: signalling in development and disease
@ast
Anaplastic lymphoma kinase: signalling in development and disease
@en
Anaplastic lymphoma kinase: signalling in development and disease
@en-gb
Anaplastic lymphoma kinase: signalling in development and disease
@nl
type
label
Anaplastic lymphoma kinase: signalling in development and disease
@ast
Anaplastic lymphoma kinase: signalling in development and disease
@en
Anaplastic lymphoma kinase: signalling in development and disease
@en-gb
Anaplastic lymphoma kinase: signalling in development and disease
@nl
prefLabel
Anaplastic lymphoma kinase: signalling in development and disease
@ast
Anaplastic lymphoma kinase: signalling in development and disease
@en
Anaplastic lymphoma kinase: signalling in development and disease
@en-gb
Anaplastic lymphoma kinase: signalling in development and disease
@nl
P2860
P921
P3181
P356
P1433
P1476
Anaplastic lymphoma kinase: signalling in development and disease
@en
P2093
Caroline Grabbe
Emma Vernersson
P275
P2860
P304
P3181
P356
10.1042/BJ20090387
P407
P577
2009-05-27T00:00:00Z
2009-06-15T00:00:00Z