PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
about
PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodiaCMS: an adapter molecule involved in cytoskeletal rearrangementsThe coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6Involvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyreneIdentification of preferred protein interactions by phage-display of the human Src homology-3 proteome.The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activationTargeting and activation of Rac1 are mediated by the exchange factor beta-Pix.ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2p21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized Rho exchange factorPak1 regulates branching morphogenesis in 3D MDCK cell culture by a PIX and beta1-integrin-dependent mechanismPak1 and PIX regulate contact inhibition during epithelial wound healingBrk activates rac1 and promotes cell migration and invasion by phosphorylating paxillinGIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnoverAffixin activates Rac1 via betaPIX in C2C12 myoblastScrib regulates PAK activity during the cell migration processNuclear import of Pin1 is mediated by a novel sequence in the PPIase domainPaxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamicsVav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation.Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathwayActivation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complexA PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassemblyGRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interactionInteraction between PAK and nck: a template for Nck targets and role of PAK autophosphorylationFunctional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complexRegulation of Bin1 SH3 domain binding by phosphoinositidesRegulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1An ADP-ribosylation factor GTPase-activating protein Git2-short/KIAA0148 is involved in subcellular localization of paxillin and actin cytoskeletal organizationTumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathwayPaxillin comes of ageDifferential regulation of pulmonary endothelial monolayer integrity by varying degrees of cyclic stretchVav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activationSynapse formation is regulated by the signaling adaptor GIT1.PAG3/Papalpha/KIAA0400, a GTPase-activating protein for ADP-ribosylation factor (ARF), regulates ARF6 in Fcgamma receptor-mediated phagocytosis of macrophagesAffixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interactionPaxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesionRegulation of small GTPases by GEFs, GAPs, and GDIsThe Rac1 hypervariable region in targeting and signaling: a tail of many stories
P2860
Q22008024-301CAC27-E930-4A3C-8991-BAF5029FA44DQ22009896-04D2820E-9277-4787-BB47-F4832AB9A718Q24290231-0E3EDE0F-F92B-404F-8647-5F3C6FB5E5E1Q24291712-BC5E1C63-A64B-40DE-9517-6BEDC44DF891Q24299721-A6FD64FE-3119-409F-83EC-3C4A50F57A92Q24303904-616EAF31-4506-4D18-9CF1-6B6849461EF3Q24305342-A740407D-6A3C-4908-8CE6-4A32BE1793CCQ24305448-9CFC7D98-0F79-48FF-A13E-7F6B50127E5CQ24309450-D15C2949-0328-403E-87BE-90D8AEFDE91AQ24311626-4C73AC85-4DEF-48A4-9169-713C2686F5FEQ24314659-FF7A562B-6133-437C-A926-2D62227ECE95Q24318315-1C34AABE-ABDD-4207-BC26-E31CC358FAC2Q24319063-C8D64502-229F-4A46-BACC-5F9AD581A44BQ24321686-274D1E15-C6AA-4AFD-A8C2-B7DD0AA78A43Q24328751-906C0F99-D720-43EF-AE6F-00F0CE187E54Q24336290-09D2A046-BDC9-4E0F-89EC-8D592DEE15C1Q24337723-07AA3FD1-8A95-4A5B-A930-3B262C23C2F4Q24515205-6FB325EC-C6A6-4C9D-8BD6-1A269F22F64DQ24524132-65A94BF6-7E7A-41AD-9CB2-C7F16BABEBCFQ24527321-E5DACA6F-B62D-4F57-9A38-89B47B0AE0C9Q24536674-2448AD85-67CD-4111-9AA7-39C3BBDD0891Q24552051-44353254-2A29-4DDE-A332-CA6DDEAD9F42Q24553130-E2140F53-140E-460D-B325-9503531696B1Q24554208-A0861075-9523-47CE-B5B9-AB85F2561EC1Q24555675-9D89C473-DEBE-4E30-B332-773D16E8661AQ24561373-157FBAD0-9468-4E9E-8E14-A47D946E83D5Q24628972-A940F2A5-016B-41AC-8993-3CA9A23A3440Q24633235-FA9FF39E-09E7-46E2-AE52-AEBFB3B294CEQ24635316-0A7E6F4A-E191-4E07-906C-D062C6409A3DQ24649739-14462D63-3595-49D9-A805-844C3814DF27Q24657852-1186DDD2-F132-4B32-BB53-532C9F171EAEQ24674945-7449A573-D7AA-49F1-BCA8-6BB09C398D1DQ24675128-C41C59B0-6795-466C-9A66-02A612EA1059Q24675182-95DE417B-D378-4AA0-9564-455B76D739A9Q24675747-EF17B7AE-35C1-43A9-97B0-09A533BC4F90Q24676556-DBB9165B-8C77-4EDB-8647-F28FB268EDD0Q24682031-5104CA60-AC07-4084-B096-B13E7D3B8C9AQ24685749-79C6E9DE-7CD0-4873-91D8-5B93F877E5D0Q26825750-5E38F9EC-6C68-459B-8E3A-6E72B0F65E64Q26864271-F75D4024-CDFB-44DA-9A3C-EC208266249E
P2860
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@ast
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@en
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@en-gb
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@nl
type
label
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@ast
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@en
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@en-gb
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@nl
prefLabel
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@ast
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@en
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@en-gb
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@nl
P2093
P3181
P1433
P1476
PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
@en
P2093
P304
P3181
P356
10.1016/S1097-2765(00)80019-2
P407
P577
1998-01-01T00:00:00Z