The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities
about
Promyelocytic leukemia isoform IV confers resistance to encephalomyocarditis virus via the sequestration of 3D polymerase in nuclear bodiesORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6New insights into the role of RNase L in innate immunityThe innate immune system of the perinatal lung and responses to respiratory syncytial virus infectionDimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral ActivityThe Mitochondrial Fission Receptor MiD51 Requires ADP as a CofactorCrystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain that antagonizes RNase L activationOASL-a new player in controlling antiviral innate immunityWhat is the oligoadenylate synthetases-like protein and does it have therapeutic potential for influenza?Interferon-Inducible Oligoadenylate Synthetase-Like Protein Acts as an Antiviral Effector against Classical Swine Fever Virus via the MDA5-Mediated Type I Interferon-Signaling Pathway.Viral phosphodiesterases that antagonize double-stranded RNA signaling to RNase L by degrading 2-5AOas1b-dependent Immune Transcriptional Profiles of West Nile Virus Infection in the Collaborative Cross.cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.Expression, purification and characterization of the interferon-inducible, antiviral and tumour-suppressor protein, human RNase L.Intracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogensRoles of retinoic acid-inducible gene-I-like receptors (RLRs), Toll-like receptor (TLR) 3 and 2'-5' oligoadenylate synthetase as viral recognition receptors on human mast cells in response to viral infection.Oral administration of Lactococcus lactis subsp. lactis JCM5805 enhances lung immune response resulting in protection from murine parainfluenza virus infectionCrystal structure and functional analysis of MiD49, a receptor for the mitochondrial fission protein Drp1.Overexpression of the transcription factor Sp1 activates the OAS-RNAse L-RIG-I pathway.Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape.Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signalingInterferon-stimulated genes and their antiviral effector functionsEPSTI1 Is Involved in IL-28A-Mediated Inhibition of HCV InfectionMild Plasmodium falciparum malaria following an episode of severe malaria is associated with induction of the interferon pathway in Malawian children.Double-Stranded RNA Is Detected by Immunofluorescence Analysis in RNA and DNA Virus Infections, Including Those by Negative-Stranded RNA Viruses.RNase L triggers autophagy in response to viral infections.Pathologic effects of RNase-L dysregulation in immunity and proliferative control.Interferon-stimulated genes-essential antiviral effectors implicated in resistance to Theiler's virus-induced demyelinating disease.Emerging roles of interferon-stimulated genes in the innate immune response to hepatitis C virus infectionActivation of RNase L is dependent on OAS3 expression during infection with diverse human virusesRole of ribonuclease L in viral pathogen-associated molecular pattern/influenza virus and cigarette smoke-induced inflammation and remodeling.Genome-wide profiling of in vivo LPS-responsive genes in splenic myeloid cells.Ifit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages.A link between adipogenesis and innate immunity: RNase-L promotes 3T3-L1 adipogenesis by destabilizing Pref-1 mRNA.Cell-type-specific effects of RNase L on viral induction of beta interferon.RNase-L control of cellular mRNAs: roles in biologic functions and mechanisms of substrate targeting.Identification of an atypical etiological head and neck squamous carcinoma subtype featuring the CpG island methylator phenotypeHuman serum RNase-L level is inversely associated with metabolic syndrome and age.Multi-level regulation of cellular recognition of viral dsRNA.Interferon-stimulated genes: roles in viral pathogenesis.
P2860
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P2860
The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The oligoadenylate synthetase ...... multiple antiviral activities
@ast
The oligoadenylate synthetase ...... multiple antiviral activities
@en
The oligoadenylate synthetase ...... multiple antiviral activities
@en-gb
The oligoadenylate synthetase ...... multiple antiviral activities
@nl
type
label
The oligoadenylate synthetase ...... multiple antiviral activities
@ast
The oligoadenylate synthetase ...... multiple antiviral activities
@en
The oligoadenylate synthetase ...... multiple antiviral activities
@en-gb
The oligoadenylate synthetase ...... multiple antiviral activities
@nl
prefLabel
The oligoadenylate synthetase ...... multiple antiviral activities
@ast
The oligoadenylate synthetase ...... multiple antiviral activities
@en
The oligoadenylate synthetase ...... multiple antiviral activities
@en-gb
The oligoadenylate synthetase ...... multiple antiviral activities
@nl
P2093
P921
P356
P1476
The oligoadenylate synthetase ...... multiple antiviral activities
@en
P2093
Helle Kristiansen
Philippe Despres
Signe Eskildsen-Larsen
P356
10.1089/JIR.2010.0107
P407
P577
2010-12-12T00:00:00Z